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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration 期刊论文
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
Authors:  Ya-Nan Geng;  Ming Zhao;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Ming Fan;  Ling-Ling Zhu
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Gypenoside-14 (GP-14)  Neuronal Damage  Hypoxia  Transcriptome Sequencing  Neuroprotection  
Gyosaponins (GPs) alleviate hypoxia-induced injury in PC12 cells and enhance tolerance to anoxia in C57BL/6 mice 期刊论文
Journal of Food Biochemistry, 2022, 期号: 0, 页码: e14448
Authors:  Cheng-Bo Wang;  Ming Zhao;  Jun Wang;  Jiao-Tai Shi;  Wei-Feng Wang;  Ying Zhang;  Xian-Hua Meng;  Chun-Yan Sang;  Ling-Ling Zhu;  Jun-Li Yang
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Gynostemma pentaphyllum (Thunb.) Makino  gypenosides  high altitude hypoxia  hypoxia tolerance  neuroprotection  
Fluorometric assay based on the in situ formation of silicon nanoparticles for the determination of β‑glucuronidase 期刊论文
Microchimica Acta, 2022, 期号: 189, 页码: 436
Authors:  Stanislas Nsanzamahoro;  Wei-Feng Wang;  Ying Zhang;  Cheng-Bo Wang;  Yan-Ping Shi;  Jun-Li Yang
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β-Glucuronidase  Dopamine  Silicon nanoparticles  Baicalin  Fluorescence  
(-)-Naringenin 4’,7-Dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain Through Inhibition of Multiple Channels 期刊论文
Molecules, 2022, 卷号: 5, 期号: 27, 页码: 1735
Authors:  Ru-Rong Gu;  Xian-Hua Meng;  Yin Zhang;  Hai-Yan Xu;  Li Zhan;  Zhao-Bing Gao;  Jun-Li Yang;  Yue-Ming Zheng
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(-)-Naringenin 40,7-dimethyl ether  analgesic candidate  mechanism study  delayed rectifier potassium currents  ion channels  
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model 期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
Authors:  Ya-Nan Geng;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Feng Yan;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Xian-Hua Meng;  Ming Fan;  Ming Zhao;  Ling-Ling Zhu
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Gypenoside  Neuroinflammation  Blood brain barrier  High altitude cerebral edema  NF-κB signaling pathway  
Four new compounds with cytotoxic and neuroprotective activity from Notopterygium incisum 期刊论文
Phytochemistry Letters, 2022, 期号: 49, 页码: 138-144
Authors:  Li-Mei Ma;  Tian Chai;  Cheng-Bo Wang;  Yi-Dan Zheng;  Li Ma;  Xian-Hua Meng;  Kai Wang;  Wei-Feng Wang;  Mahdi Moridi Farimani;  Chun-Yan Sang;  Jun-Li Yang
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Notopterygium incisum  Umbelliferae  Chemical constituents  Cytotoxicity  Neuroprotective effect  
Nardoguaianone L isolated from Nardostachys jatamansi improved the effect of gemcitabine chemotherapy via regulating AGE signaling pathway in SW1990 cells 期刊论文
Molecules, 2022, 期号: 27, 页码: 6849
Authors:  Yi-Dan Zheng;  Li-Mei Ma;  Jin-Jian Lu;  Tian Chai;  Mohammad Reza Naghavi;  Jun-Yi Ma;  Chun-Yan Sang;  Jun-Li Yang
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pancreatic cancer  gemcitabine  proteomic  AGE-RAGE signaling pathway  SW1990 cells  
Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis 期刊论文
Electrophoresis, 2019, 卷号: 40, 期号: 16-17, 页码: 2075–2083
Authors:  Wei-Feng Wang;  Jun-Li Yang
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Capillary electrophoresis  Enzyme inhibitor  Immobilization  Screening