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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration 期刊论文
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
Authors:  Ya-Nan Geng;  Ming Zhao;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Ming Fan;  Ling-Ling Zhu
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Gypenoside-14 (GP-14)  Neuronal Damage  Hypoxia  Transcriptome Sequencing  Neuroprotection  
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model 期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
Authors:  Ya-Nan Geng;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Feng Yan;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Xian-Hua Meng;  Ming Fan;  Ming Zhao;  Ling-Ling Zhu
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Gypenoside  Neuroinflammation  Blood brain barrier  High altitude cerebral edema  NF-κB signaling pathway  
Dammarane-Type Saponins from Gynostemma pentaphyllum Prevent Hypoxia-Induced Neural Injury through Activation of ERK, Akt, and CREB Pathways 期刊论文
Journal of Agricultural and Food Chemistry, 2020, 卷号: 68, 期号: 1, 页码: 193−205
Authors:  Wang J(王君);  Zhao M(赵名);  Xiang Cheng;  Ying Han;  Tong Zhao;  Ming Fan;  Zhu LL(朱玲玲);  Yang JL(杨军丽)
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Gynostemma pentaphyllum  dammarane-type saponins  hypoxia-induced neural injury