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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration 期刊论文
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
Authors:  Ya-Nan Geng;  Ming Zhao;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Ming Fan;  Ling-Ling Zhu
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Gypenoside-14 (GP-14)  Neuronal Damage  Hypoxia  Transcriptome Sequencing  Neuroprotection  
Gyosaponins (GPs) alleviate hypoxia-induced injury in PC12 cells and enhance tolerance to anoxia in C57BL/6 mice 期刊论文
Journal of Food Biochemistry, 2022, 期号: 0, 页码: e14448
Authors:  Cheng-Bo Wang;  Ming Zhao;  Jun Wang;  Jiao-Tai Shi;  Wei-Feng Wang;  Ying Zhang;  Xian-Hua Meng;  Chun-Yan Sang;  Ling-Ling Zhu;  Jun-Li Yang
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Gynostemma pentaphyllum (Thunb.) Makino  gypenosides  high altitude hypoxia  hypoxia tolerance  neuroprotection  
Terpenoids from Nardostachys jatamansi and Their Cytotoxic Activity against Human Pancreatic Cancer Cell Lines 期刊论文
Phytochemistry, 2022, 期号: 200, 页码: 113228
Authors:  Li-Mei Ma;  Kai Wang;  Xian-Hua Meng;  Yi-Dan Zheng;  Cheng-Bo Wang;  Tian Chai;  Mohammad Reza Naghavi;  Chun-Yan Sang;  Jun-Li Yang
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Nardostachys jatamansi DC.  Valerianaceae  Terpenoids  Cytotoxicity  Human pancreatic cancer cell lines  
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model 期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
Authors:  Ya-Nan Geng;  Jun-Li Yang;  Xiang Cheng;  Ying Han;  Feng Yan;  Cheng-Bo Wang;  Xiu-Fang Jiang;  Xian-Hua Meng;  Ming Fan;  Ming Zhao;  Ling-Ling Zhu
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Gypenoside  Neuroinflammation  Blood brain barrier  High altitude cerebral edema  NF-κB signaling pathway