A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells

doi:10.1016/j.talanta.2015.10.026

LICP OpenIR > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells
Department	中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
	Wang JM(王佳敏)1,2,3 ; Ni Y(倪月)1,2,3; Shao SJ(邵士俊)1,2 ; Shao SJ(邵士俊)
	2016
Source Publication	Talanta
ISSN	0039-9140
Volume	147 Pages:468-472
Abstract	Based on the reversible redox reaction of 4-amino-2,2,6,6-tetramethyl-piperidin-1-ol with oxidative ClO⁻ and reductive ascorbic acid (AA), a reversible fluorescent probe, incorporating 4-amino-2,2,6,6-tetramethyl-piperidin-1-ol group into a 7-nitrobenzoxadiazole (NBD) fluorophore, was synthesized and studied for the cyclic detection of ClO⁻/AA in aqueous solution. The NBD-based probe displayed sensitive and selective On–Off–On fluorescent responses to ClO⁻/AA and was successfully applied to monitor the ClO⁻/AA redox cycle in living HeLa cells under physiological conditions.
Keyword	Fluorescent Probe 7-nitrobenzoxadiazole (Nbd) Redox Cycle Clo- Bioimaging
Subject Area	分析化学与药物化学
DOI	10.1016/j.talanta.2015.10.026
Funding Organization	the National Natural Science Foundation of China (20972170;21275150);the Funds for Distinguished Young Scientists of Gansu (1210RJDA013)
Indexed By	SCI
If	4.162
Language	英语
Funding Project	药物分子识别研究组
compositor	第一作者单位
Citation statistics	Cited Times:45[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.licp.cn/handle/362003/19142
Collection	中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Corresponding Author	Shao SJ(邵士俊)
Affiliation	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation GB/T 7714	Wang JM,Ni Y,Shao SJ,et al. A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells[J]. Talanta,2016,147:468-472.
APA	Wang JM,Ni Y,Shao SJ,&邵士俊.(2016).A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells.Talanta,147,468-472.
MLA	Wang JM,et al."A reversible fluorescence probe for detection of ClO-/AA redox cycle in aqueous solution and in living cells".Talanta 147(2016):468-472.

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