| Temperature-assisted ionic liquid dispersive liquid-liquid microextraction combined with high performance liquid chromatography for the determination of anthraquinones in Radix et Rhizoma Rhei samples | |
| Department | 甘肃省天然药物重点实验室 |
Zhang HF(张洪飞); Shi YP(师彦平)
| |
| 2010 | |
| Source Publication | Talanta
 |
| ISSN | 0039-9140 |
| Volume | 82Pages:1010-1016 |
| Abstract | In this article, a novel method termed as temperature-assisted ionic liquid dispersive liquid–liquid microextraction (TA IL-DLLME) combining high performance liquid chromatography with diode array detection (HPLC-DAD) was developed for the determination of anthraquinones in Radix et Rhizoma Rhei samples. The ionic liquid (1-hexyl-3-methylimidazolium hexafluorophosphate) was used to replace volatile organic solvent as an extraction solvent for the extraction of anthraquinones (aloe-emodin, rhein, emodin, chrysophanol and physcion) from Radix et Rhizoma Rhei. Several important parameters influencing the extraction efficiency of TA IL-DLLME such as the type and volume of extraction solvent and disperser solvent, sample pH, extraction time, extraction temperature, centrifugation time as well as salting-out effects were optimized. Under the optimal conditions, the spiked recovery for each analyte was in the range of 95.2–108.5%. The precisions of the proposed method were varied from 1.1% to 4.4% (RSD). All the analytes exhibited good linearity with correlation coefficients (r2) ranging from 0.9986 to 0.9996. The limits of detection for all target analytes were ranged from 0.50 to 2.02_gL−1 (S/N = 3). The experimental results indicated that the proposed method was successfully applied to the analysis of anthraquinones in Radix et Rhizoma Rhei. |
| Keyword | Temperature-assisted Ionic Liquid Dispersive Liquid–liquid Microextraction High Performance Liquid Chromatography Anthraquinones Radix Et Rhizoma Rhei Samples |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Key Technology Research and Development Program of China (No. 2007BAI37B05);National Natural Science Foundation of China (No. 20875095) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1196 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Recommended Citation GB/T 7714 | Zhang HF,Shi YP. Temperature-assisted ionic liquid dispersive liquid-liquid microextraction combined with high performance liquid chromatography for the determination of anthraquinones in Radix et Rhizoma Rhei samples[J]. Talanta,2010,82:1010-1016. |
| APA | 张洪飞,&师彦平.(2010).Temperature-assisted ionic liquid dispersive liquid-liquid microextraction combined with high performance liquid chromatography for the determination of anthraquinones in Radix et Rhizoma Rhei samples.Talanta,82,1010-1016. |
| MLA | 张洪飞,et al."Temperature-assisted ionic liquid dispersive liquid-liquid microextraction combined with high performance liquid chromatography for the determination of anthraquinones in Radix et Rhizoma Rhei samples".Talanta 82(2010):1010-1016. |
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