LICP OpenIR  > 固体润滑国家重点实验室(LSL)
A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing
Department固体润滑国家重点实验室
Fan ZJ(范增杰)1; Liu B(刘斌)2; Wang JQ(王金清)1; Zhang SY(张松营)2; Lin QQ(林茜茜)2; Gong PW(公培伟)1; Ma LM(马立民)1; Yang SR(杨生荣)1; Wang JQ(王金清)
2014
Source PublicationAdvanced Functional Materials
ISSN1616-301X
Volume24Issue:25Pages:3933-3943
AbstractAvoiding wound infection and retaining an appropriate level of moisture around woundz are major challenges in wound care management. Therefore, designing hydrogels with desired antibacterial performance and good water-maintaining ability is of particular significance to promote the development of wound dressing. Thus a series of hydrogels are prepared by crosslinking of Ag/graphene composites with acrylic acid and N,N'-methylene bisacrylamide at different mass ratios. The antibacterial performance and accelerated wound-healing ability of hydrogel are systematically evaluated with the aim of attaining a novel and effective wound dressing. The as-prepared hydrogel with the optimal Ag to graphene mass ratio of 5:1 (Ag5G1) exhibits stronger antibacterial abilities than other hydrogels. Meanwhile, Ag5G1 hydrogel exhibits excellent biocompatibility, high swelling ratio, and good extensibility. More importantly, in vivo experiments indicate that Ag5G1 hydrogel can significantly accelerate the healing rate of artificial wounds in rats, and histological examination reveals that it helps to successfully reconstruct intact and thickened epidermis during 15 day of healing of impaired wounds. In one word, the present approach can shed new light on designing of antibacterial material like Ag/graphene composite hydrogel with promising applications in wound dressing.
Subject Area材料科学与物理化学
DOI10.1002/adfm.201304202
Funding Organizationthe National Natural Science Foundation of China (Grant Nos. 51205385;51075384);“Top Hundred Talents Program” of Chinese Academy of Sciences
Indexed BySCI
If11.805
Language英语
Funding Project聚合物摩擦学组
compositor第一作者单位
Citation statistics
Cited Times:634[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/6961
Collection固体润滑国家重点实验室(LSL)
Corresponding AuthorWang JQ(王金清)
Affiliation1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
2.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Fan ZJ,Liu B,Wang JQ,et al. A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing[J]. Advanced Functional Materials,2014,24(25):3933-3943.
APA Fan ZJ.,Liu B.,Wang JQ.,Zhang SY.,Lin QQ.,...&王金清.(2014).A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing.Advanced Functional Materials,24(25),3933-3943.
MLA Fan ZJ,et al."A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing".Advanced Functional Materials 24.25(2014):3933-3943.
Files in This Item:
File Name/Size DocType Version Access License
1 FZJ-AFM 2014.pdf(4996KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Fan ZJ(范增杰)]'s Articles
[Liu B(刘斌)]'s Articles
[Wang JQ(王金清)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Fan ZJ(范增杰)]'s Articles
[Liu B(刘斌)]'s Articles
[Wang JQ(王金清)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Fan ZJ(范增杰)]'s Articles
[Liu B(刘斌)]'s Articles
[Wang JQ(王金清)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 1 FZJ-AFM 2014.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.