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Bio-inspired encapsulation and functionalization of living cells with artificial shells
Department固体润滑国家重点实验室
Wang S(王莎)1,2; Guo ZG(郭志光)1,2; Guo ZG(郭志光)
2014
Source PublicationColloids and Surfaces B: Biointerfaces
ISSN0927-7765
Volume113Pages:483-500
AbstractIn nature, most single cells do not have structured shells to provide extensive protection apart from diatoms and radiolarians. Fabrication of biomimetic structures based on living cells encapsulated with artificial shells has a great impact on the area of cell-based sensors and devices as well as fundamental studies in cell biology. The past decade has witnessed a rapid increase of research concerning the new fabrication strategies, functionalization and applications of this kind of encapsulated cells. In this review, the latest fabrication strategies on how to encapsulate living cells with functional shells based on the diversity of artificial shells are discussed: hydrogel matrix shells, sal-gel shells, polymeric shells, and induced mineral shells. Classical different types of artificial shells are introduced and their advantages and disadvantages are compared and explained. The biomedical applications of encapsulated cells with particular emphasis on cell implant protection, cell separation, biosensors, cell therapy and tissue engineering are also described and a recap of this review and the future perspectives on these active areas is given finally.
KeywordBio-inspired Living Cells Artificial Shells Encapsulation Functional
Subject Area材料科学与物理化学
DOI10.1016/j.colsurfb.2013.09.024
Funding Organizationthe National Nature Science Foundation of China (NO. 31070155;11172301;21203217);the “Fundsfor Distinguished Young Scientists” of Hubei Province (ZRZ0048);the “Western Light Talent Culture” Project;the Co-joint Project of Chinese Academy of Sciences;the “Top Hundred Talents” Program of Chinese Academy of Sciences
Indexed BySCI
If4.152
Language英语
Funding Project空间润滑材料组
compositor第二作者单位
Citation statistics
Cited Times:32[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/6892
Collection固体润滑国家重点实验室(LSL)
Corresponding AuthorGuo ZG(郭志光)
Affiliation1.Hubei Univ, Key Lab Green Preparat & Applicat Funct Mat, Minist Educ, Wuhan 430062, Peoples R China
2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Wang S,Guo ZG,Guo ZG. Bio-inspired encapsulation and functionalization of living cells with artificial shells[J]. Colloids and Surfaces B: Biointerfaces,2014,113:483-500.
APA Wang S,Guo ZG,&郭志光.(2014).Bio-inspired encapsulation and functionalization of living cells with artificial shells.Colloids and Surfaces B: Biointerfaces,113,483-500.
MLA Wang S,et al."Bio-inspired encapsulation and functionalization of living cells with artificial shells".Colloids and Surfaces B: Biointerfaces 113(2014):483-500.
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