| Biocompatibility of HAP/Ti gradient coating by microarc oxidation and biomimetic process | |
| Department | 固体润滑国家重点实验室 |
Zhang D(张东); Zhang BP(张宝萍); Li ZG(李志革); Wang L(王琳); Liu B(刘斌); Wang JQ(王金清)
| |
| 2011 | |
| Source Publication | Advanced Materials Research
 |
| ISSN | 1662-8985 |
| Volume | 177Pages:325-328 |
| Abstract | This study is to evaluate the biocompatibility of HAP/Ti gradient coating by microarc oxidation and biomimetic process. Titanium alloys were activated by microarc oxidation (MAO), and immersed in simulated body fluid to prepare HAP/Ti gradient coating. Scanning electron microscopy (SEM) had been used to investigate the microstructure of the coatings. The biocompatibility of the coatings was evaluated by animal acute and subacute toxicity test, micronucleus test, hemolysis test, and oral mucosa test. The results showed HAP/Ti gradient coating was successfully fabricated on the substrate. The animal experiment showed the coating had not short-term toxicity, oral mucosa irritation, and micronucleus occurrence rate was 3.2 ‰ and hemolysis rate was 2.5%. The HAP/Ti gradient coating made by MAO and biomimetic process showed good bio-security and compatibility, it may be new oral implant materials. |
| Keyword | Titanium Alloys Micro-arc Oxidation Hap Biocompatibility |
| Subject Area | 材料科学与物理化学 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 聚合物摩擦学组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/654 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liu B(刘斌) |
| Recommended Citation GB/T 7714 | Zhang D,Zhang BP,Li ZG,et al. Biocompatibility of HAP/Ti gradient coating by microarc oxidation and biomimetic process[J]. Advanced Materials Research,2011,177:325-328. |
| APA | 张东,张宝萍,李志革,王琳,刘斌,&王金清.(2011).Biocompatibility of HAP/Ti gradient coating by microarc oxidation and biomimetic process.Advanced Materials Research,177,325-328. |
| MLA | 张东,et al."Biocompatibility of HAP/Ti gradient coating by microarc oxidation and biomimetic process".Advanced Materials Research 177(2011):325-328. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 2011325-328.PDF（5269KB） | 开放获取 | License | View Application Full Text | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment