| A novel imidazolium-based organic-silica hybrid monolith for per aqueous capillary electrochromatography | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Tang S(汤胜)1,2,3 ; Liu SJ(刘淑娟)1,2; Ren HX(任海霞)1,2,3; Liang XJ(梁晓静)1,2; Qiu HD(邱洪灯)1,2; Guo Y(郭勇)1,2; Liu X(刘霞)1,2; Jiang SX(蒋生祥)1,2; Guo Y(郭勇); Jiang SX(蒋生祥)
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| 2014 | |
| Source Publication | RSC Advances
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| ISSN | 2046-2069 |
| Volume | 4Issue:49Pages:25819-25826 |
| Abstract | A new imidazolium-based organic-silica hybrid monolith by binding the imidazole-1-acetic acid onto the surface of monolithic silica was prepared through a simple route. The obtained monolith exhibited per aqueous capillary electrochromatography (PACEC) characteristics in water-rich mobile phases. A typical per aqueous chromatography behavior was observed for the test solutes (an increase in H2O content resulted in an increase in retention). The effects of water content, pH and ion strength of mobile phase on the retention of test compounds in highly aqueous eluents were investigated in detail. PACEC in itself is a green chromatography mode that makes green capillary electrochromatography possible. Various hydrophilic compounds including amino acids were baseline separated with enhanced resolution of the obtained monolith under PACEC mode. It is evidenced that solutes were retained predominantly by hydrophobic interactions under PACEC conditions. Therefore, PACEC has the potential to replace hydrophilic interaction chromatography and meanwhile it is complementary to the reverse-phase chromatography. |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1039/c4ra03460k |
| Funding Organization | the National Nature Science Foundation of China (no. 21175143;21105107;20905072);the National Science & Technology Major Project of China (no. 2011ZX05010;2011ZX05011) |
| Indexed By | SCI |
| If | 3.840 |
| Language | 英语 |
| Funding Project | 药物分离材料研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/6542 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Guo Y(郭勇); Jiang SX(蒋生祥) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Tang S,Liu SJ,Ren HX,et al. A novel imidazolium-based organic-silica hybrid monolith for per aqueous capillary electrochromatography[J]. RSC Advances,2014,4(49):25819-25826. |
| APA | Tang S.,Liu SJ.,Ren HX.,Liang XJ.,Qiu HD.,...&蒋生祥.(2014).A novel imidazolium-based organic-silica hybrid monolith for per aqueous capillary electrochromatography.RSC Advances,4(49),25819-25826. |
| MLA | Tang S,et al."A novel imidazolium-based organic-silica hybrid monolith for per aqueous capillary electrochromatography".RSC Advances 4.49(2014):25819-25826. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 2014-RSC ADV-Tang sh（432KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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