| NHC-Pd complex-catalyzed double carbonylation of aryl iodides with secondary amines to α-keto amides | |
| Department | OSSO国家重点实验室 |
Zheng SZ(郑书展); Wang Y(汪妍); Zhang CY(张春艳) ; Liu JH(刘建华); Xia CG(夏春谷); Liu JH(刘建华); Xia CG(夏春谷)
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| 2014 | |
| Source Publication | Applied Organometallic Chemistry
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| ISSN | 0268-2605 |
| Volume | 28Issue:1Pages:48-53 |
| Abstract | A series of palladium–NHC compounds were prepared and their catalytic activity in the double carbonylation of aryl iodides to synthesize α-keto amides were examined. Palladium complexes bearing mixed NHC–phosphine exhibited high efficiency for the double carbonylation reaction. The effects of different solvents, base, temperature, carbon monoxide (CO), pressure, various amine and aryl iodides were investigated. Both electron-rich and electron-deficient aryl iodides afforded the corresponding substituted α-keto amides in moderate to good yields. A possible mechanism was also proposed. |
| Keyword | N-heterocyclic Carbene Palladium Complexes Double Carbonylation Aryl Iodides Α-keto Amides |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1002/aoc.3075 |
| Funding Organization | the National Natural Science Foundation of China (21073209;21133011) |
| Indexed By | SCI |
| If | 2.248 |
| Language | 英语 |
| Funding Project | 均相催化课题组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/6522 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Liu JH(刘建华); Xia CG(夏春谷) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| Recommended Citation GB/T 7714 | Zheng SZ,Wang Y,Zhang CY,et al. NHC-Pd complex-catalyzed double carbonylation of aryl iodides with secondary amines to α-keto amides[J]. Applied Organometallic Chemistry,2014,28(1):48-53. |
| APA | Zheng SZ.,Wang Y.,Zhang CY.,Liu JH.,Xia CG.,...&夏春谷.(2014).NHC-Pd complex-catalyzed double carbonylation of aryl iodides with secondary amines to α-keto amides.Applied Organometallic Chemistry,28(1),48-53. |
| MLA | Zheng SZ,et al."NHC-Pd complex-catalyzed double carbonylation of aryl iodides with secondary amines to α-keto amides".Applied Organometallic Chemistry 28.1(2014):48-53. |
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| NHC-Pd complex-catal（437KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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