| Asymmetric Addition of Terminal Alkynes to N-(Diphenylphosphinoyl)imines Promoted by Stoichiometric Amounts of a Proline-Derived beta-Amino Alcohol | |
| Department | 羰基合成与选择氧化国家重点实验室 |
| Yan WJ(阎文锦); Mao B(毛斌); Zhu SQ(朱绍群); Jiang XX(蒋先兴); Liu ZL(刘中立); Wang R(王锐) | |
| 2009 | |
| Source Publication | European Journal of Organic Chemistry
 |
| ISSN | 1466-8033 |
| Pages | 3790-3794 |
| Abstract | A new synthetic methodology for the preparation of optically active propargylamines is described. The alkynylation of aromatic, heteroaromatic, aliphatic and α,β-unsaturated N-(diphenylphosphinoyl) imines was investigated by using diethylzinc and a proline-derived β-amino alcohol. N-(Diphenyl-phosphinoyl)-protected propargylic amines can be synthesized in high yields and with good to excellent enantioselectivities. |
| Keyword | Enantioslectivity Asymmetric Synthesis Alkynylation Β-amino Alcohol Propargylamines |
| Subject Area | 物理化学 |
| Funding Organization | the National Natural Science Foundation of China (20525206;20772052;90813012;20621091);the Chang Jiang Program of the Ministry of Education of China |
| Indexed By | SCI |
| Language | 英语 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/556 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Wang R(王锐) |
| Recommended Citation GB/T 7714 | Yan WJ,Mao B,Zhu SQ,et al. Asymmetric Addition of Terminal Alkynes to N-(Diphenylphosphinoyl)imines Promoted by Stoichiometric Amounts of a Proline-Derived beta-Amino Alcohol[J]. European Journal of Organic Chemistry,2009:3790-3794. |
| APA | 阎文锦,毛斌,朱绍群,蒋先兴,刘中立,&王锐.(2009).Asymmetric Addition of Terminal Alkynes to N-(Diphenylphosphinoyl)imines Promoted by Stoichiometric Amounts of a Proline-Derived beta-Amino Alcohol.European Journal of Organic Chemistry,3790-3794. |
| MLA | 阎文锦,et al."Asymmetric Addition of Terminal Alkynes to N-(Diphenylphosphinoyl)imines Promoted by Stoichiometric Amounts of a Proline-Derived beta-Amino Alcohol".European Journal of Organic Chemistry (2009):3790-3794. |
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| 39_Eur.J.Org.Chem.20（237KB） | 开放获取 | License | View Application Full Text | |||
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