| General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves | |
| Department | OSSO国家重点实验室 |
| Sun N(孙楠)1; Hong LF(洪灵芬)1; Huang, Fang1; Ren H(任鸿)1; Mo WM(莫卫民)1; Hu BX(胡宝祥)1; Shen ZL(沈振陆)1; Hu XQ(胡信全)1,2; Hu XQ(胡信全) | |
| 2013 | |
| Source Publication | Tetrahedron
 |
| ISSN | 0040-4020 |
| Volume | 69Issue:19Pages:3927-3933 |
| Abstract | A general and efficient method for the synthesis of 2,3-unsubstituted indoles has been established by the intramolecular cyclization of N-benzyl 2-anilinoacetals. Acidic mesoporous molecular sieve (MCM-41-SO3H) has shown excellent catalytic activity on this transformation, and the 2,3-unsubstituted indoles bearing 7-substituent or strong electron-withdrawing substituents also could be achieved by this protocol. Moreover, the heterogeneous catalyst, MCM-41-SO3H, could be conveniently recovered and reused without obvious loss of the catalytic activity. This work will provide an economic and environmentalbenign method for the construction of various indole derivatives. |
| Keyword | N-benzyl 2-anilinoacetals 2 Heterogeneous Catalysis 3-unsubstituted Indoles Mcm-41-so3h Mesoporous Molecular Sieve Shape/size Selectivity |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1016/j.tet.2013.03.026 |
| Funding Organization | the National Natural Science Foundation of China (No. 20772111;20876149);the Key Innovation Team Project of Zhejiang Province, China (No. 2009R50002) |
| Indexed By | SCI |
| If | 2.817 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/4969 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Hu XQ(胡信全) |
| Affiliation | 1.Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Sun N,Hong LF,Huang, Fang,et al. General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves[J]. Tetrahedron,2013,69(19):3927-3933. |
| APA | Sun N.,Hong LF.,Huang, Fang.,Ren H.,Mo WM.,...&胡信全.(2013).General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves.Tetrahedron,69(19),3927-3933. |
| MLA | Sun N,et al."General and efficient synthesis of 2,3-unsubstituted indoles catalyzed by acidic mesoporous molecular sieves".Tetrahedron 69.19(2013):3927-3933. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Tetrahedron 69 (2013（655KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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