| Merging the ring opening of benzoxazoles with secondary amines and an iron-catalyzed oxidative cyclization towards the environmentally friendly synthesis of 2-aminobenzoxazoles | |
| Department | OSSO国家重点实验室 |
Xu DQ(徐大乾); Wang, Wenfang; Miao CX(苗成霞) ; Zhang QH(张巧红); Xia CG(夏春谷); Sun W(孙伟); Sun W(孙伟)
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| 2013 | |
| Source Publication | Green Chemistry
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| ISSN | 1463-9262 |
| Volume | 15Issue:10Pages:2975-2980 |
| Abstract | A facile and environmentally friendly method was developed through merging the ring opening of benzoxazoles with secondary amines and an iron-catalyzed oxidative cyclization towards the synthesis of 2-aminobenzoxazoles. In the oxidative cyclization step, with catalytic amounts of FeCl and aqueous H2O2 as a green oxidant, highly desirable 2-aminobenzoxazoles were isolated in excellent yields of up to 97%. A plausible radical process is proposed for the oxidative cyclization on the basis of mechanistic studies. |
| DOI | 10.1039/c3gc41206g |
| Funding Organization | the Chinese Academy of Sciences;the National Natural Science Foundation of China (21133011;21103207;21103206) |
| Indexed By | SCI |
| If | 6.852 |
| Language | 英语 |
| Funding Project | 生物与仿生催化课题组;均相催化课题组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/4763 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Sun W(孙伟) |
| Affiliation | Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Xu DQ,Wang, Wenfang,Miao CX,et al. Merging the ring opening of benzoxazoles with secondary amines and an iron-catalyzed oxidative cyclization towards the environmentally friendly synthesis of 2-aminobenzoxazoles[J]. Green Chemistry,2013,15(10):2975-2980. |
| APA | Xu DQ.,Wang, Wenfang.,Miao CX.,Zhang QH.,Xia CG.,...&孙伟.(2013).Merging the ring opening of benzoxazoles with secondary amines and an iron-catalyzed oxidative cyclization towards the environmentally friendly synthesis of 2-aminobenzoxazoles.Green Chemistry,15(10),2975-2980. |
| MLA | Xu DQ,et al."Merging the ring opening of benzoxazoles with secondary amines and an iron-catalyzed oxidative cyclization towards the environmentally friendly synthesis of 2-aminobenzoxazoles".Green Chemistry 15.10(2013):2975-2980. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Green Chemistry 2975（228KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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