| Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds | |
| Department | 固体润滑国家重点实验室 |
Qi YY(齐园园)1,2; Tai ZX(邰志新)1,3; Sun DF(孙东飞)1,3; Chen JT(陈江涛)1 ; Ma HB(马海斌)1,2; Yan XB(阎兴斌)1; Liu B(刘斌)2; Xue QJ(薛群基)1; Yan XB(阎兴斌); Liu B(刘斌)
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| The second department | 清洁能源化学与材料实验室 |
| 2013 | |
| Source Publication | Journal of Applied Polymer Science
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| ISSN | 0021-8995 |
| Volume | 127Issue:3Pages:1885-1894 |
| Abstract | Nanofibrous biocomposite scaffolds of poly(vinyl alcohol) (PVA) and graphene oxide (GO) were prepared by using electrospinning method. The microstructure, crystallinity, and morphology of the scaffolds were characterized through X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The mechanical properties were investigated by tensile testing. Moreover, Mouse Osteoblastic Cells (MC3T3-E1) attachment and proliferation on the nanofibrous scaffolds were investigated by MTT [3-(4,5-dimeth-ylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay, SEM observation and fluorescence staining. XRD and FTIR results verify the presence of GO in the scaffolds. SEM images show the three-dimensional porous fibrous morphology, and the average diameter of the composite fibers decreases with increasing the content of GO. The mechanical properties of the scaffolds are altered by changing the content of GO as well. The tensile strength and elasticity modulus increase when the content of GO is lower than 1 wt %, but decrease when GO is up to 3 and 5 wt %. MC3T3-E1 cells attach and grow on the surfaces of the scaffolds, and the adding of GO do not affect the cells' viability. Also, MC3T3-E1 cells are likely to spread on the PVA/GO composite scaffolds. Above all, these unique features of the PVA/GO nanofibrous scaffolds prepared by electrospinning would open up a wide variety of future applications in bone tissue engineering and drug delivery systems. |
| Keyword | Poly(Vinyl Alcohol) Graphene Oxide Nanofiber Biocomposite Electrospinning |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1002/app.37924 |
| Funding Organization | the National Natural Science Foundation of China, (Grant no.51005225);the Top Hundred Talents Program of Chinese Academy of Sciences |
| Indexed By | SCI |
| If | 1.640 |
| Language | 英语 |
| Funding Project | 低维材料与化学储能课题组;低维材料摩擦学组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/4628 |
| Collection | 固体润滑国家重点实验室（LSL） 清洁能源化学与材料实验室 |
| Corresponding Author | Yan XB(阎兴斌); Liu B(刘斌) |
| Affiliation | 1.Chinese Acad Sci, State Key Lab Solid Lubricat, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100080, Peoples R China |
| Recommended Citation GB/T 7714 | Qi YY,Tai ZX,Sun DF,et al. Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds[J]. Journal of Applied Polymer Science,2013,127(3):1885-1894. |
| APA | Qi YY.,Tai ZX.,Sun DF.,Chen JT.,Ma HB.,...&刘斌.(2013).Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds.Journal of Applied Polymer Science,127(3),1885-1894. |
| MLA | Qi YY,et al."Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds".Journal of Applied Polymer Science 127.3(2013):1885-1894. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 齐园园 1.395.pdf（1102KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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