| Chromatographic Evaluation of Octadecyl-Bonded SiO2/SiO2-Based Stationary Phase for Reversed-Phase High Performance Liquid Chromatography | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Zhang X(张霞)1,2,3 ; Zhang ZX(张志欣)1,2; Wang LT(王利涛)1,2; Liu Q(刘芹)1,2; Zhang XL(张晓莉)1,2,3; Dong SQ(董树清)1,2; Zhao L(赵亮)1,2; Zhao L(赵亮)
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| 2013 | |
| Source Publication | Journal of Inorganic and Organometallic Polymers and Materials
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| ISSN | 1574-1443 |
| Volume | 23Issue:6Pages:1445-1450 |
| Abstract | A new type of octadecyl-bonded SiO2/SiO2 (ODSS) core-shell monodisperse silica spheres was prepared as a high performance liquid chromatography stationary phase. The chromatographic performance was evaluated and compared with totally porous octadecyl-bonded SiO2. Various methods were used for characterization of the two column packings for reversed-phase chromatography in terms of permeability, hydrophobic selectivity, sensitivity, stability and hydrophobicity. The results showed that the ODSS-based stationary phase has enhanced permeability, good hydrophobic selectivity, high chemical stability and sensitivity. Acidic, basic and neutral aromatic compounds were separated on the two types of stationary phases. The ODSS-based stationary phase has good selectivity and gives symmetrical narrow peaks under reversed-phase conditions. |
| Keyword | Core–shell Microspheres Hplc Octadecyl-bonded Sio2/sio2 Stationary Phase Octadecyl-bonded Sio2 Stationary Phase Reversed-phase |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1007/s10904-013-9947-1 |
| Funding Organization | the National Nature Science Foundation of China (Grant: 20675085);Science and Technology Support Xinjiang Project (2010);the Science and Technology Special Project of Lanzhou (No. 2010-1-156) |
| Indexed By | SCI |
| If | 1.077 |
| Language | 英语 |
| Funding Project | 药物手性分离研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/4581 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Zhao L(赵亮) |
| Affiliation | 1.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Key Lab Nat Med Gansu Prov, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang X,Zhang ZX,Wang LT,et al. Chromatographic Evaluation of Octadecyl-Bonded SiO2/SiO2-Based Stationary Phase for Reversed-Phase High Performance Liquid Chromatography[J]. Journal of Inorganic and Organometallic Polymers and Materials,2013,23(6):1445-1450. |
| APA | Zhang X.,Zhang ZX.,Wang LT.,Liu Q.,Zhang XL.,...&赵亮.(2013).Chromatographic Evaluation of Octadecyl-Bonded SiO2/SiO2-Based Stationary Phase for Reversed-Phase High Performance Liquid Chromatography.Journal of Inorganic and Organometallic Polymers and Materials,23(6),1445-1450. |
| MLA | Zhang X,et al."Chromatographic Evaluation of Octadecyl-Bonded SiO2/SiO2-Based Stationary Phase for Reversed-Phase High Performance Liquid Chromatography".Journal of Inorganic and Organometallic Polymers and Materials 23.6(2013):1445-1450. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 20131445-1450.pdf（235KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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