| Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral a-branched heteroaryl amines | |
| Department | 羰基合成与选择氧化国家重点实验室 |
| Zhang JL(张金龙); Yang YH(杨玉红); Wang M(王梅); Lin L(林利); Wang R(王锐) | |
| 2012 | |
| Source Publication | Tetrahedron Letters
 |
| ISSN | 0040-4039 |
| Volume | 53Pages:6893-6896 |
| Abstract | This work concerns the asymmetric additions of benzothiazole to a variety of N-tert-butanesulfinyl imines with excellent diastereoselectivities (d.r. up to >99:1). Amino alkoxyl lithium was the key additive to obtain the excellent diastereoselectivity. More functionalized 4-methyl-5-vinyl thiazole and alkyl imines which can isomerize to enamines are also compatible substrates to the present protocol. |
| Keyword | Asymmetric Synthesis Benzothiazole Diarylmethylamine Diastereoselectivity N-tert-butanesulfinyl Imine |
| Subject Area | 物理化学 |
| Funding Organization | NSFC (nos. 21002043;21272107;20932003);the National S&T Major Project of China (2012ZX09504-001-003);Fundamental Research Funds for the Central Universities (lzujbky-2010-184) |
| Indexed By | SCI |
| Language | 英语 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/3882 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Lin L(林利); Wang R(王锐) |
| Recommended Citation GB/T 7714 | Zhang JL,Yang YH,Wang M,et al. Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral a-branched heteroaryl amines[J]. Tetrahedron Letters,2012,53:6893-6896. |
| APA | 张金龙,杨玉红,王梅,林利,&王锐.(2012).Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral a-branched heteroaryl amines.Tetrahedron Letters,53,6893-6896. |
| MLA | 张金龙,et al."Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral a-branched heteroaryl amines".Tetrahedron Letters 53(2012):6893-6896. |
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| B39.Tetrahedron Lett（553KB） | 开放获取 | CC BY-NC-SA | View Application Full Text | |||
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