| Catalytic asymmetric construction of tetrasubstituted carbon stereocenters by conjugate addition of dialkyl phosphine oxides to beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds | |
| Department | OSSO国家重点实验室 |
| Zhao DP(赵德鹏)2; Mao LJ(毛丽娟)2; Wang LQ(王林清)2; Yang DX(杨东旭)2; Wang R(王锐)1,2; Wang R(王锐) | |
| 2012 | |
| Source Publication | Chemical Communications
 |
| ISSN | 1359-7345 |
| Volume | 48Issue:6Pages:889-891 |
| Abstract | The catalytic asymmetric phospha-Michael reaction of dialkyl phosphine oxides with beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds was achieved. The products bearing tetrasubstituted carbon stereocenters were obtained in high yields with excellent enantioselectivities (up to >99% ee). |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1039/c1cc16079f |
| Funding Organization | the National Natural Science Foundation of China (no. 90813012;20932003);the Key National S&T Program “Major New Drug Development” of the Ministry of Science and Technology (2012ZX09504001-003) |
| Indexed By | SCI |
| If | 6.378 |
| Language | 英语 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/3803 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Wang R(王锐) |
| Affiliation | 1.State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, P.R. China 2.Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, State Key Laboratory of Applied Organic Chemistry, and Institute of Biochemistry and Molecular Biology, Lanzhou University, Lanzhou, P. R. China |
| Recommended Citation GB/T 7714 | Zhao DP,Mao LJ,Wang LQ,et al. Catalytic asymmetric construction of tetrasubstituted carbon stereocenters by conjugate addition of dialkyl phosphine oxides to beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds[J]. Chemical Communications,2012,48(6):889-891. |
| APA | Zhao DP,Mao LJ,Wang LQ,Yang DX,Wang R,&王锐.(2012).Catalytic asymmetric construction of tetrasubstituted carbon stereocenters by conjugate addition of dialkyl phosphine oxides to beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds.Chemical Communications,48(6),889-891. |
| MLA | Zhao DP,et al."Catalytic asymmetric construction of tetrasubstituted carbon stereocenters by conjugate addition of dialkyl phosphine oxides to beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds".Chemical Communications 48.6(2012):889-891. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 22.Chem. Commun., 20（1130KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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