| Highly enantioselective reduction of ketones by chiral diol-modified lithium aluminum hydride reagents | |
| Department | 绿色化学与催化研发中心 ; OSSO国家重点实验室 |
Ren YL(任运来); Tian XZ(田信哲); Sun KP(孙鲲鹏) ; Xu J(许健); Xu XL(徐贤伦); Lv SJ(吕士杰)
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| 2006 | |
| Source Publication | Tetrahedron Letters
 |
| ISSN | 0040-4039 |
| Volume | 47Issue:4Pages:463-465 |
| Abstract | Some readily available chiral diols from indene and (D)-mannitol were investigated as chiral modifiers in lithium aluminum hydride reduction of ketones, and it was discovered that further modification of these reducing reagents by a simple a-amino alcohol resulted in a remarkable increase in optical yield. Among the investigated chiral modifiers, chiral diol I gave the highest enantio selectivities. |
| Keyword | Asymmetric Reduction Ketone Diol Lithium Tetrahydridoaluminate |
| Subject Area | 物理化学 |
| Funding Organization | National Nature Science Foundation of China (No. 29933050) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 精细石油化工催化课题组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/3684 |
| Collection | 绿色化学研究发展中心 |
| Corresponding Author | Xu XL(徐贤伦) |
| Recommended Citation GB/T 7714 | Ren YL,Tian XZ,Sun KP,et al. Highly enantioselective reduction of ketones by chiral diol-modified lithium aluminum hydride reagents[J]. Tetrahedron Letters,2006,47(4):463-465. |
| APA | 任运来,田信哲,孙鲲鹏,许健,徐贤伦,&吕士杰.(2006).Highly enantioselective reduction of ketones by chiral diol-modified lithium aluminum hydride reagents.Tetrahedron Letters,47(4),463-465. |
| MLA | 任运来,et al."Highly enantioselective reduction of ketones by chiral diol-modified lithium aluminum hydride reagents".Tetrahedron Letters 47.4(2006):463-465. |
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| File Name/Size | DocType | Version | Access | License | ||
| 任运来Tetrahedron Lette（88KB） | 开放获取 | License | View Application Full Text | |||
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