| Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane | |
| Department | 固体润滑国家重点实验室 |
Ma HB(马海斌)1,3; Su WX(苏文新)2; Tai ZX(邰志新)1; Sun DF(孙东飞)1; Yan XB(阎兴斌)1 ; Liu B(刘斌)2; Xue QJ(薛群基)1; Yan XB(阎兴斌)
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| 2012 | |
| Source Publication | Chinese Science Bulletin
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| ISSN | 1001-6538 |
| Volume | 57Issue:23Pages:3051-3058 |
| Abstract | A series of polylactic acid (PLA) based nanocomposite fibrous membranes, including neat PLA, PLA/hydroxyapatite (HA) and PLA/HA/graphene oxide (GO), were fabricated via electrospinning method. The morphology and composition were investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) respectively. The thermal stability was determined by thermogravimetric analysis (TGA). To estimate the cytocompatibility of asprepared PLA/HA/GO fibrous membrane, MC3T3-E1 cells were cultured, and the corresponding cell adhesion and differentiation capability were investigated by fluorescence microscopy, SEM and MTT test. The electrospun ternary PLA/HA/GO membrane exhibited three-dimensional fibrous structure with relatively rough surface morphology, which made itself ideal for cell attachment and proliferation in bone tissue regeneration. The fluorescence microscopy, SEM and MTT test confirmed that the PLA/HA/GO nanocomposite fibrous membrane created a proper environment for the seeding and proliferation of MC3T3-E1 cells. |
| Keyword | Polylactic Acid Hydroxyapatite Graphene Oxide Fibrous Membranes |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1007/s11434-012-5336-3 |
| Funding Organization | the Hundred Talents Program of Chinese Academy of Sciences;the National Natural Science Foundation of China (51005225) |
| Indexed By | SCI |
| If | 1.319 |
| Language | 英语 |
| Funding Project | 低维材料摩擦学组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/3316 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Yan XB(阎兴斌) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 3.Gansu Prov Hosp Tradit Chinese Med, Lanzhou 730050, Peoples R China |
| Recommended Citation GB/T 7714 | Ma HB,Su WX,Tai ZX,et al. Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane[J]. Chinese Science Bulletin,2012,57(23):3051-3058. |
| APA | Ma HB.,Su WX.,Tai ZX.,Sun DF.,Yan XB.,...&阎兴斌.(2012).Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane.Chinese Science Bulletin,57(23),3051-3058. |
| MLA | Ma HB,et al."Preparation and cytocompatibility of polylactic acid/hydroxyapatite/graphene oxide nanocomposite fibrous membrane".Chinese Science Bulletin 57.23(2012):3051-3058. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 3051-3058.PDF（1430KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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