Aerobic Synthesis and Nucleophilicity of 2,3-Dihydroindolizines | |
Department | 羰基合成与选择氧化国家重点实验室(OSSO) |
Su YJ(苏毅进) | |
The second department | 苏毅进人才团队 |
2023-12 | |
Source Publication | ChemistrySelect |
Volume | 8Issue:46Pages:e202302537 |
Abstract | Herein, we reported a practical and metal-free synthesis of 2,3-dihydroindolizines using N-alkyl pyridinium salts and electron-deficient alkenes with ambient air as a sole oxidant. Interestingly, a halogen bond donor (penta-fluoroiodobenzene 20 mol %) was successfully applied to promote this partial oxidation by slowing down the undesired decomposition processes, probably because of the formation of a halogen-bonded adduct. Moreover, the C1 position of 2,3-dihydroindolizines was utilized as a good nucleophile for nucleophilic aromatic substitution with 4-iodo-1-methylpyridin-1-ium trifluoromethanesulfonate as electrophile and provided a new-type dipyridinium compound effectively. |
DOI | 10.1002/slct.202302537 |
If | 2.1 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/30585 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Recommended Citation GB/T 7714 | Su YJ. Aerobic Synthesis and Nucleophilicity of 2,3-Dihydroindolizines[J]. ChemistrySelect,2023,8(46):e202302537. |
APA | Su YJ.(2023).Aerobic Synthesis and Nucleophilicity of 2,3-Dihydroindolizines.ChemistrySelect,8(46),e202302537. |
MLA | Su YJ."Aerobic Synthesis and Nucleophilicity of 2,3-Dihydroindolizines".ChemistrySelect 8.46(2023):e202302537. |
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