Iron-Catalyzed Borylation of Ketones to α-Hydroxyboronates | |
Department | 羰基合成与选择氧化国家重点实验室(OSSO) |
Zhu Q(朱庆); Xia CG(夏春谷); Liu C(刘超) | |
The second department | 刘超课题组 |
2021 | |
Source Publication | Chinese Journal of Organic Chemistry |
Volume | 41Issue:2Pages:661-669 |
Abstract | Fe-catalyzed borylation of ketones to access tertiary α-hydroxyboronates has been demonstrated. In this transformation, commercially available FeBr2 was used as the catalyst, alcohols have been added to accelerate the transformation and avoid the side reaction. Various aliphatic ketones with different functional groups have been converted into tertiary α-hydroxyboronates. This transformation showed a particular tolerance for ketones with steric hinderance, which was distinguished from the traditional Cu catalyst. A gram scale reaction was also available. The alcoholic C—O functionalizations based on α-hydroxyboronates have been realized to access tertiary alkyl boronic esters, gem-diborylalkanes and gemsilylborylalkanes. |
Keyword | iron catalyst α-hydroxyboronates borylation ketones |
If | 1.652 |
compositor | 第一作者单位 |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/27484 |
Collection | 羰基合成与选择氧化国家重点实验室(OSSO) |
Corresponding Author | Liu C(刘超) |
Recommended Citation GB/T 7714 | Zhu Q,Xia CG,Liu C. Iron-Catalyzed Borylation of Ketones to α-Hydroxyboronates[J]. Chinese Journal of Organic Chemistry,2021,41(2):661-669. |
APA | Zhu Q,Xia CG,&Liu C.(2021).Iron-Catalyzed Borylation of Ketones to α-Hydroxyboronates.Chinese Journal of Organic Chemistry,41(2),661-669. |
MLA | Zhu Q,et al."Iron-Catalyzed Borylation of Ketones to α-Hydroxyboronates".Chinese Journal of Organic Chemistry 41.2(2021):661-669. |
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