| Critical-Size Defects of Animal Models for Bone Regeneration | |
Lv, Zhao-Yong1; Chen, Xi-Meng2; Zhang, Yu-Jue1; Li, June1; Zhao, Zhong-Hui1; Li, Ke-Yi1; Xie, Guan-Nan1; Liu, Feng-Zhen1,3; Zhang, Bin1
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| 2018-06-01 | |
| Corresponding Author | Xie, Guan-Nan() ; Liu, Feng-Zhen() ; Zhang, Bin() |
| Source Publication | JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING
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| ISSN | 2157-9083 |
| Volume | 8Issue:6Pages:761-770 |
| Abstract | Animal models have been extensively used and have contributed greatly to the development and establishment of a wide range of translational approaches aiming to regenerate the bone tissue. Accordingly, this paper presents a review of the critical-size defects (CSDs) of animal models for bone repair and contributes to determine which defect dimensions could be considered as being critical size. Recent work involving the definition of CSDs, CSDs related animal models for bone regeneration, and an overview of the evaluation of bone regeneration in the critical size defects has been summarized and reviewed. A systematic review were conducted to provide prerequisite data for establishing bone critical size defect model in different animals and evaluating bone materials using these models and guide future clinical trials of bone tissue engineering, more importantly, determine the estimates and the effect for guiding future human clinical trials. Also, there is a necessity for further standardization of the animal models to enable more accurate comparison among future studies. |
| Keyword | Critical-Size Defects Animal Models Bone Regeneration Review |
| DOI | 10.1166/jbt.2018.1821 |
| Funding Organization | Science Foundation of Shandong Province of China ; Medicine and health Science technology development plan of Shandong Province of China |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Science Foundation of Shandong Province of China[ZR2017PH056] ; Science Foundation of Shandong Province of China[ZR2017PH037] ; Medicine and health Science technology development plan of Shandong Province of China[2017WS503] |
| WOS Research Area | Cell Biology |
| Publisher | AMER SCIENTIFIC PUBLISHERS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/27213 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Xie, Guan-Nan; Liu, Feng-Zhen; Zhang, Bin |
| Affiliation | 1.Liaocheng Univ, Liaocheng Peoples Hosp, Med Coll, Liaocheng 252000, Peoples R China 2.Dongchangfu Liaocheng Peoples Hosp, Liaocheng 252000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Gansu, Peoples R China |
| Recommended Citation GB/T 7714 | Lv, Zhao-Yong,Chen, Xi-Meng,Zhang, Yu-Jue,et al. Critical-Size Defects of Animal Models for Bone Regeneration[J]. JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,2018,8(6):761-770. |
| APA | Lv, Zhao-Yong.,Chen, Xi-Meng.,Zhang, Yu-Jue.,Li, June.,Zhao, Zhong-Hui.,...&Zhang, Bin.(2018).Critical-Size Defects of Animal Models for Bone Regeneration.JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,8(6),761-770. |
| MLA | Lv, Zhao-Yong,et al."Critical-Size Defects of Animal Models for Bone Regeneration".JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING 8.6(2018):761-770. |
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