A simple gradient equilibrium method for better separation in countercurrent chromatography | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Kaijun, Quan; Xingjun, Xi; Xinyi, Huang; Wenda, Duan; Dong, Pei; Duolong, Di | |
2018 | |
Source Publication | Journal of Separation Science |
Volume | 41Issue:20Pages:3863-3870 |
Abstract | The stationary phase retention is one of the most important parameters in countercurrent chromatography. In this work, a simple gradient equilibrium method was developed to further improve the stationary phase retention based on the optimized condition in the traditional equilibrium model. Meanwhile, this novel gradient equilibrium method was used to separate three flavone model compounds and compared with the conventional isocratic equilibrium method to evaluate the separation efficiency. The results show that better resolution or shorter separation time could be achieved with gradient equilibrium compared to isocratic equilibrium. So this novel equilibrium method has enormous potential for obtaining a better separation or saving the separating time in the preparative separation of target compounds. |
If | 2.415 |
Language | 英语 |
compositor | 第一作者单位 |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/24589 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Xinyi, Huang; Duolong, Di |
Affiliation | 1.CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, LICP, CAS 2.University of the Chinese Academy of Sciences 3.Food and Agriculture Standardization Institute, China National Institute of Standardization |
Recommended Citation GB/T 7714 | Kaijun, Quan,Xingjun, Xi,Xinyi, Huang,et al. A simple gradient equilibrium method for better separation in countercurrent chromatography[J]. Journal of Separation Science,2018,41(20):3863-3870. |
APA | Kaijun, Quan,Xingjun, Xi,Xinyi, Huang,Wenda, Duan,Dong, Pei,&Duolong, Di.(2018).A simple gradient equilibrium method for better separation in countercurrent chromatography.Journal of Separation Science,41(20),3863-3870. |
MLA | Kaijun, Quan,et al."A simple gradient equilibrium method for better separation in countercurrent chromatography".Journal of Separation Science 41.20(2018):3863-3870. |
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2018-A simple gradie(1359KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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