| Catalytic Asymmetric Huisgen Alkyne-Azide Cycloaddition of Bisalkynes by Copper(I) Nanoparticles | |
| Department | 苏州研究院 |
| Chen, Mu-Yi1; Xu, Zheng1; Chen, Li1; Song, Tao1; Zheng, Zhan-Jiang1; Cao, Jian1; Cui, Yu-Ming1; Xu LW(徐利文)1,2; Xu LW(徐利文) | |
| The second department | osso国家重点实验室 |
| 2018 | |
| Source Publication | ChemCatChem
 |
| ISSN | 1867-3880 |
| Volume | 10Issue:1Pages:280-286 |
| Abstract | The use of chiral ligands to tune the reactivity and enantioselectivity of transition‐metal catalyst for asymmetric transformations is a central challenge in synthetic organic chemistry. In this manuscript, chiral P‐ligand (Tao‐Phos)‐assisted Cu2O‐nanoparticles‐catalyzed asymmetric azide–alkyne Huisgen cycloaddition is reported. The unique features of Tao‐Phos were determined in the copper‐catalyzed desymmetrization of pyrazolone‐derived bisalkynes through catalytic asymmetric Huisgen [3+2] cycloaddition (CAHC). This CAHC transformation resulted in good yields with moderate to high enantioselectivities. |
| Keyword | Alkynes Asymmetric Catalysis Copper Cycloaddition p Ligands |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1002/cctc.201701336 |
| Funding Organization | the National Natural Science Foundation of China (No. 21472031;21503060;21773051);Zhejiang Provincial Natural Science Foundation of China (LR14B030001;LY16E030009;LY17B030005;LY17E030003) |
| Indexed By | SCI |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/23774 |
| Collection | 苏州研究院 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Xu LW(徐利文) |
| Affiliation | 1.Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education Hangzhou Normal University No.1378 Wenyi West Road, Hangzhou 311121 (P.R. China) 2.Suzhou Research Insititue and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 (P.R. China) |
| Recommended Citation GB/T 7714 | Chen, Mu-Yi,Xu, Zheng,Chen, Li,et al. Catalytic Asymmetric Huisgen Alkyne-Azide Cycloaddition of Bisalkynes by Copper(I) Nanoparticles[J]. ChemCatChem,2018,10(1):280-286. |
| APA | Chen, Mu-Yi.,Xu, Zheng.,Chen, Li.,Song, Tao.,Zheng, Zhan-Jiang.,...&徐利文.(2018).Catalytic Asymmetric Huisgen Alkyne-Azide Cycloaddition of Bisalkynes by Copper(I) Nanoparticles.ChemCatChem,10(1),280-286. |
| MLA | Chen, Mu-Yi,et al."Catalytic Asymmetric Huisgen Alkyne-Azide Cycloaddition of Bisalkynes by Copper(I) Nanoparticles".ChemCatChem 10.1(2018):280-286. |
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| File Name/Size | DocType | Version | Access | License | ||
| Chen_et_al-2018-Chem（1276KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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