| The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film | |
| Department | 固体润滑国家重点实验室 |
Liu YJ(刘义军); Luo J(罗佳); Liu B(刘斌); Zhang JY(张俊彦)
| |
| 2011 | |
| Source Publication | Applied Surface Science
 |
| ISSN | 0169-4332 |
| Volume | 257Pages:6429-6434 |
| Abstract | The objective of the present study is to preliminarily explore the effect of surface chemistry modifica- tion of Ti6Al4V with a fluorine-contained copolymer thin film on the cellular behavior of osteoblasts. A fluorine-contained random copolymer thin film was fabricated on Ti6Al4V substrate, and then char- acterized by X-ray photoelectron spectroscopy (XPS), contact angle meter and surface profiler. The results showed that the surfacemodification of Ti6Al4V alloy could simultaneously transformthe surface chemical constitution and reduce the surface energy evidently. However, the surface morphology and roughness of the Ti6Al4V substrate were hardly changed after the modification. By immersion process with simulated body fluid (SBF) and then by in vitro cytotoxicity test with MC3T3-E1 osteoblasts, the fluorine-contained copolymer thin filmexhibited desirable stability and admirable cytocompatibility. In conclusion, the fluorine-contained copolymer thin filmcould be easily applied inmodifying various solid surfaces, and the as-fabricated film also has potential applications in biomedical field. |
| Keyword | Copolymer Thin FIlm Ti6al4v Cytocompatibility Osteoblast |
| Subject Area | 材料科学与物理化学 |
| Funding Organization | the NationalNatural Science Foundation of China (grant nos. 50823008;20673131);“Hundreds Talent Program” of Chinese Academy of Sciences |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 纳米润滑研究组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/2328 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liu B(刘斌); Zhang JY(张俊彦) |
| Recommended Citation GB/T 7714 | Liu YJ,Luo J,Liu B,et al. The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film[J]. Applied Surface Science,2011,257:6429-6434. |
| APA | 刘义军,罗佳,刘斌,&张俊彦.(2011).The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film.Applied Surface Science,257,6429-6434. |
| MLA | 刘义军,et al."The cytocompatibility investigation of Ti6Al4V modified with a fluorine-contained copolymer thin film".Applied Surface Science 257(2011):6429-6434. |
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| 20116429-6434.PDF（1099KB） | 开放获取 | License | View Application Full Text | |||
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