| Asymmetric total synthesis of (-)-cladospolide B | |
| Department | 羰基合成与选择氧化国家重点实验室 |
| Wang WK(王文宽); Zhang JY(张基勇); He JM(何金梅); Tang SB(唐仕兵); Wang XL(王晓磊); She XG(厍学功); Pan XF(潘鑫复) | |
| 2008 | |
| Source Publication | Chinese J. Chem.
 |
| ISSN | 1001-604X |
| Volume | 26Issue:6Pages:1109-1113 |
| Abstract | An enantioselective total synthesis of (－)-cladospolide B was described. The key steps in this synthesis include (a) a Sharpless asymmetric dihydroxylation to elaborate syn diol at C-4 and C-5 positions; (b) a Mitsunobu esterification to reverse the configuration at C-11 from (S) to (R); and (c) a ring-closing metathesis to access the 12-membered macrocyclic ring. |
| Keyword | (－)-cladospolide b Sharpless Asymmetric Dihydroxylation Mitsunobu Esterification Ring-closing Metathesis |
| Subject Area | 物理化学 |
| Funding Organization | the Special Doctorial Program Funds of the Ministry of Education of China (No. 20040730008);National Natural Science Foundation of China (QT program, No. 20572037);NCET-05-0879;the Key Grant Project of Ministry of Education of China (No. 105169);Gansu Science Foundation (No. 3ZS051-A25-004) |
| Indexed By | SCI |
| Language | 英语 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/2265 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | She XG(厍学功); Pan XF(潘鑫复) |
| Recommended Citation GB/T 7714 | Wang WK,Zhang JY,He JM,et al. Asymmetric total synthesis of (-)-cladospolide B[J]. Chinese J. Chem.,2008,26(6):1109-1113. |
| APA | 王文宽.,张基勇.,何金梅.,唐仕兵.,王晓磊.,...&潘鑫复.(2008).Asymmetric total synthesis of (-)-cladospolide B.Chinese J. Chem.,26(6),1109-1113. |
| MLA | 王文宽,et al."Asymmetric total synthesis of (-)-cladospolide B".Chinese J. Chem. 26.6(2008):1109-1113. |
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