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Asymmetric Synthesis of Glutamic Acid Derivatives by Silver-Catalyzed Conjugate Addition-Elimination Reactions
Department苏州研究院
Yuan, Yang1; Yu, Bo1; Bo XF(柏惺峰)1; Xu, Zheng1; Zheng ZJ(郑战江)1; Cui, Yu-Ming1; Cao, Jian1; Xu LW(徐利文)1,2; Xu LW(徐利文); Zheng ZJ(郑战江)
The second departmentosso国家重点实验室
2017
Source PublicationOrganic Letters
ISSN1523-7060
Volume19Issue:18Pages:4896-4899
Abstract

The enantioselective construction of a family of chiral glycine-derived aldimino esters is described. The asymmetric tandem conjugate addition–elimination procedure is characterized by its exceptional mild reaction conditions and features with an exquisite enantioselectivity profile using commercially available silver/DTBM-SegPhos catalyst, allowing for the facile preparation of a variety of substituted and chiral glutamic acid derivatives (up to 99% ee) bearing Schiff base in a straightforward manner.

Subject Area物理化学与绿色催化
DOI10.1021/acs.orglett.7b02378
Funding Organizationthe National Natural Science Foundation of China (Nos. 21472031;21503060;21702211;21773051);Zhejiang Provincial Natural Science Foundation of China (LR14B030001;LY17E030003;LY17B030005)
Indexed BySCI
If6.579
Language英语
compositor第二作者单位
Citation statistics
Cited Times:17[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/22514
Collection苏州研究院
羰基合成与选择氧化国家重点实验室(OSSO)
Corresponding AuthorXu LW(徐利文); Zheng ZJ(郑战江)
Affiliation1.Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou 311121, P. R. China
2.Suzhou Research Institute and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China
Recommended Citation
GB/T 7714
Yuan, Yang,Yu, Bo,Bo XF,et al. Asymmetric Synthesis of Glutamic Acid Derivatives by Silver-Catalyzed Conjugate Addition-Elimination Reactions[J]. Organic Letters,2017,19(18):4896-4899.
APA Yuan, Yang.,Yu, Bo.,Bo XF.,Xu, Zheng.,Zheng ZJ.,...&郑战江.(2017).Asymmetric Synthesis of Glutamic Acid Derivatives by Silver-Catalyzed Conjugate Addition-Elimination Reactions.Organic Letters,19(18),4896-4899.
MLA Yuan, Yang,et al."Asymmetric Synthesis of Glutamic Acid Derivatives by Silver-Catalyzed Conjugate Addition-Elimination Reactions".Organic Letters 19.18(2017):4896-4899.
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