Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata) | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Zhao, Jian-Qiang1; Wang YM(王衍明)2; Yang, Yan-Long3; Zeng, Ying3; Mei, Li-Juan1; Shi YP(师彦平)2; Tao, Yan-Duo1; Shi YP(师彦平) | |
2017 | |
Source Publication | Food Chemistry |
ISSN | 0308-8146 |
Volume | 230Pages:117-124 |
Abstract | The young leaves and shoots of Sibiraea laevigata, known as "Liucha", are used as tea by Tibetans to improve digestion after meals. Long-term consumption of "Liucha" will cause weight loss. In present work, we reported on the isolation and NMR and chemical analysis-based elucidation of seven new sorbitol-O-caffeic acid ester derivatives named sorbitol esters A G (1-7) and eighteen known phenolic compounds from S. laevigata. All of the isolates were evaluated for their antioxidant and α-glucosidase inhibitory activities. Among them sorbitol ester A (1), sorbitol ester D (4), sorbitol ester F (6), sorbitol ester G (7), isoferulic acid (15), methyl caffeate (18), trans-p-hydroxycinnamic acid (19), and kaempferol 3-O-β-D-(6 ''-E-p-coumaroyl)-glucopyranoside (25) showed more potent α-glucosidase inhibitory activity than the clinical drug acarbose. |
Keyword | Sibiraea Laevigata Sorbitol O-caffeic Acid Ester Derivatives Phenolic Compounds Antioxidants Alpha-glucosidase Inhibitors |
Subject Area | 分析化学与药物化学 |
DOI | 10.1016/j.foodchem.2017.03.024 |
Funding Organization | the Significant Science & Technological Project of Qinghai Province (2014-GX-A3A);the Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences (ZSTH-027) |
Indexed By | SCI |
If | 4.529 |
Language | 英语 |
Funding Project | 药物化学成分研究组 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/22159 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Tao, Yan-Duo; Shi YP(师彦平) |
Affiliation | 1.ey Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, PR China 2.Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China 3.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China |
Recommended Citation GB/T 7714 | Zhao, Jian-Qiang,Wang YM,Yang, Yan-Long,et al. Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata)[J]. Food Chemistry,2017,230:117-124. |
APA | Zhao, Jian-Qiang.,Wang YM.,Yang, Yan-Long.,Zeng, Ying.,Mei, Li-Juan.,...&师彦平.(2017).Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata).Food Chemistry,230,117-124. |
MLA | Zhao, Jian-Qiang,et al."Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata)".Food Chemistry 230(2017):117-124. |
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