Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata)
Department中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Zhao, Jian-Qiang1; Wang YM(王衍明)2; Yang, Yan-Long3; Zeng, Ying3; Mei, Li-Juan1; Shi YP(师彦平)2; Tao, Yan-Duo1; Shi YP(师彦平)
2017
Source PublicationFood Chemistry
ISSN0308-8146
Volume230Pages:117-124
Abstract

The young leaves and shoots of Sibiraea laevigata, known as "Liucha", are used as tea by Tibetans to improve digestion after meals. Long-term consumption of "Liucha" will cause weight loss. In present work, we reported on the isolation and NMR and chemical analysis-based elucidation of seven new sorbitol-O-caffeic acid ester derivatives named sorbitol esters A G (1-7) and eighteen known phenolic compounds from S. laevigata. All of the isolates were evaluated for their antioxidant and α-glucosidase inhibitory activities. Among them sorbitol ester A (1), sorbitol ester D (4), sorbitol ester F (6), sorbitol ester G (7), isoferulic acid (15), methyl caffeate (18), trans-p-hydroxycinnamic acid (19), and kaempferol 3-O-β-D-(6 ''-E-p-coumaroyl)-glucopyranoside (25) showed more potent α-glucosidase inhibitory activity than the clinical drug acarbose.

KeywordSibiraea Laevigata Sorbitol O-caffeic Acid Ester Derivatives Phenolic Compounds Antioxidants Alpha-glucosidase Inhibitors
Subject Area分析化学与药物化学
DOI10.1016/j.foodchem.2017.03.024
Funding Organizationthe Significant Science & Technological Project of Qinghai Province (2014-GX-A3A);the Project of Discovery, Evaluation and Transformation of Active Natural Compounds, Strategic Biological Resources Service Network Programme of Chinese Academy of Sciences (ZSTH-027)
Indexed BySCI
If4.529
Language英语
Funding Project药物化学成分研究组
compositor第二作者单位
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/22159
Collection中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Corresponding AuthorTao, Yan-Duo; Shi YP(师彦平)
Affiliation1.ey Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, PR China
2.Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China
3.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China
Recommended Citation
GB/T 7714
Zhao, Jian-Qiang,Wang YM,Yang, Yan-Long,et al. Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata)[J]. Food Chemistry,2017,230:117-124.
APA Zhao, Jian-Qiang.,Wang YM.,Yang, Yan-Long.,Zeng, Ying.,Mei, Li-Juan.,...&师彦平.(2017).Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata).Food Chemistry,230,117-124.
MLA Zhao, Jian-Qiang,et al."Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata)".Food Chemistry 230(2017):117-124.
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