RGDC Peptide-Induced Biomimetic Calcium Phosphate Coating Formed on AZ31 Magnesium Alloy | |
Department | 固体润滑国家重点实验室 |
Cao, Lin1; Wang, Lina1; Fan, Lingying1; Xiao, Wenjun1; Lin, Bingpeng1; Xu, Yimeng1; Liang J(梁军)2; Cao, Baocheng1 | |
2017 | |
Source Publication | Materials |
ISSN | 1996-1944 |
Volume | 10Issue:4Pages:358(1-15) |
Abstract | Magnesium alloys as biodegradable metal implants have received a lot of interest in biomedical applications. However, magnesium alloys have extremely high corrosion rates a in physiological environment, which have limited their application in the orthopedic field. In this study, calcium phosphate compounds (Ca–P) coating was prepared by arginine–glycine–aspartic acid–cysteine (RGDC) peptide-induced mineralization in 1.5 simulated body fluid (SBF) to improve the corrosion resistance and biocompatibility of the AZ31 magnesium alloys. The adhesion of Ca–P coating to the AZ31 substrates was evaluated by a scratch test. Corrosion resistance and cytocompatibility of the Ca–P coating were investigated. The results showed that the RGDC could effectively promote the nucleation and crystallization of the Ca–P coating and the Ca–P coating had poor adhesion to the AZ31 substrates. The corrosion resistance and biocompatibility of the biomimetic Ca–P coating Mg alloys were greatly improved compared with that of the uncoated sample. |
Keyword | Biomimetic Calcium Phosphate Coating Rgdc Magnesium Alloy Corrosion Resistance Biocompatibility |
Subject Area | 材料科学与物理化学 |
DOI | 10.3390/ma10040358 |
Funding Organization | the Natural Science Foundation of Gansu Province, China (grant No. 1208RJZA236);the Key Technology Support Program of Gansu Province, China (grant No. 1604FKCA089) |
Indexed By | SCI |
If | 2.654 |
Language | 英语 |
Funding Project | 空间润滑材料研究组 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/21996 |
Collection | 固体润滑国家重点实验室(LSL) |
Corresponding Author | Cao, Baocheng |
Affiliation | 1.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Cao, Lin,Wang, Lina,Fan, Lingying,et al. RGDC Peptide-Induced Biomimetic Calcium Phosphate Coating Formed on AZ31 Magnesium Alloy[J]. Materials,2017,10(4):358(1-15). |
APA | Cao, Lin.,Wang, Lina.,Fan, Lingying.,Xiao, Wenjun.,Lin, Bingpeng.,...&Cao, Baocheng.(2017).RGDC Peptide-Induced Biomimetic Calcium Phosphate Coating Formed on AZ31 Magnesium Alloy.Materials,10(4),358(1-15). |
MLA | Cao, Lin,et al."RGDC Peptide-Induced Biomimetic Calcium Phosphate Coating Formed on AZ31 Magnesium Alloy".Materials 10.4(2017):358(1-15). |
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materials-10-00358-v(6400KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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