Facile synthesis of enzyme functional metal-organic framework for colorimetric detecting H2O2 and ascorbic acid | |
Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Gao CJ(高存继)1; Zhu HM(朱红梅)2; Chen J(陈佳)1; Qiu HD(邱洪灯)1; Qiu HD(邱洪灯) | |
2017 | |
Source Publication | Chinese Chemical Letters |
ISSN | 1001-8417 |
Volume | 28Issue:5Pages:1006-1012 |
Abstract | In this work, a metal-organic frameworks material MIL-88 was prepared easily using solvent-thermal method, and was first found to have catalytic activities similar to those of biological enzymes such as catalase and peroxidase. The material was characterized by XRD, SEM, TEM, EDX, FT-IR techniques and an N2 adsorption method. It exhibited peroxidase-like activity through catalytic oxidation of the peroxidase substrate 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of H2O2, producing a blue-colored solution. Under optimal conditions, the absorbance at 652 nm is linearly correlated with the concentration of H2O2 from 2.0 × 10−6 mol/L to 2.03 × 10−5 mol/L (R2 = 0.981) with a detection limit of 5.62 × 10−7 mol/L (S/N = 3). More importantly, a sensitive and selective method for ascorbic acid detection was developed using this material as a catalyst. The analytical method for ascorbic acid detection was observed to have a linear range from 2.57 × 10−6 mol/L to 1.01 × 10−5 mol/L (R2 = 0.989) with a detection limit of 1.03 × 10−6 mol/L (S/N = 3). This work suggests MOFs have advantages of preparing biomimetic catalysts and extends applications of the functional MOFs in the field of biosensor. |
Keyword | Metal-organic Frameworks Horseradish Peroxidase H2o2 Ascorbic Acid Colorimetric Detection Biomimetic Catalyst |
Subject Area | 分析化学与药物化学 |
DOI | 10.1016/j.cclet.2017.02.011 |
Funding Organization | the Funds for Distinguished Young Scientists of Gansu (No. 1506RJDA281);the top priority program of “One-Three-Five” Strategic Planning of Lanzhou Institute of Chemical Physics, CAS;the Foundation for Sci&Tech Research Project of Gansu Province (No. 1606RJYA307) |
Indexed By | SCI |
If | 1.932 |
Language | 英语 |
Funding Project | 药物分离材料研究组 |
compositor | 第一作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/21794 |
Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Corresponding Author | Qiu HD(邱洪灯) |
Affiliation | 1.Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China 2.Institute of Microbiology and Biochemical Pharmacy, School of Pharmacy, Lanzhou University, Lanzhou 730000, China |
Recommended Citation GB/T 7714 | Gao CJ,Zhu HM,Chen J,et al. Facile synthesis of enzyme functional metal-organic framework for colorimetric detecting H2O2 and ascorbic acid[J]. Chinese Chemical Letters,2017,28(5):1006-1012. |
APA | Gao CJ,Zhu HM,Chen J,Qiu HD,&邱洪灯.(2017).Facile synthesis of enzyme functional metal-organic framework for colorimetric detecting H2O2 and ascorbic acid.Chinese Chemical Letters,28(5),1006-1012. |
MLA | Gao CJ,et al."Facile synthesis of enzyme functional metal-organic framework for colorimetric detecting H2O2 and ascorbic acid".Chinese Chemical Letters 28.5(2017):1006-1012. |
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