P(O)R-2-Directed Enantioselective C-H Olefination toward Chiral Atropoisomeric Phosphine-Olefin Compounds

doi:10.1021/acs.orglett.7b00608

	P(O)R-2-Directed Enantioselective C-H Olefination toward Chiral Atropoisomeric Phosphine-Olefin Compounds
Department	OSSO国家重点实验室
	Li, Shi-Xia 1; Ma YN(马艳娜)1; Yang SD(杨尚东)1,2; Yang SD(杨尚东)
	2017
Source Publication	Organic Letters
ISSN	1523-7060
Volume	19 Issue:7 Pages:1842-1845
Abstract	An effective synthesis of chiral atropoisomeric biaryl phosphine–olefin compounds via palladium-catalyzed enantioselective C–H olefination has been developed for the first time. The reactions are operationally simple, tolerate wide functional groups, and have a good ee value. Notably, P(O)R₂ not only acts as the directing group to direct C–H activation in order to make a useful ligand but also serves to facilitate composition of the product in a useful manner in this transformation.
Subject Area	物理化学与绿色催化
DOI	10.1021/acs.orglett.7b00608
Funding Organization	the NSFC (Nos. 21472076;21532001);PCSIRT (IRT_15R28;lzujbky-2016-ct02)
Indexed By	SCI
Language	英语
compositor	第二作者单位
Citation statistics	Cited Times:86[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.licp.cn/handle/362003/21789
Collection	羰基合成与选择氧化国家重点实验室（OSSO）
Corresponding Author	Yang SD(杨尚东)
Affiliation	1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
Recommended Citation GB/T 7714	Li, Shi-Xia,Ma YN,Yang SD,et al. P(O)R-2-Directed Enantioselective C-H Olefination toward Chiral Atropoisomeric Phosphine-Olefin Compounds[J]. Organic Letters,2017,19(7):1842-1845.
APA	Li, Shi-Xia,Ma YN,Yang SD,&杨尚东.(2017).P(O)R-2-Directed Enantioselective C-H Olefination toward Chiral Atropoisomeric Phosphine-Olefin Compounds.Organic Letters,19(7),1842-1845.
MLA	Li, Shi-Xia,et al."P(O)R-2-Directed Enantioselective C-H Olefination toward Chiral Atropoisomeric Phosphine-Olefin Compounds".Organic Letters 19.7(2017):1842-1845.

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