Synthesis of Polyfunctional Pyridines via Copper-Catalyzed Oxidative Coupling Reactions
DepartmentERC国家工程研究中心
Fu YJ(付亚杰)1; Wang PP(王盼盼)1; Guo X(郭鑫)1; Wu P(吴萍)1; Meng X(孟旭)2; Chen BH(陈保华)1; Chen BH(陈保华)
The second departmentosso国家重点实验室
2016
Source PublicationJournal of Organic Chemistry
ISSN0022-3263
Volume81Issue:23Pages:11671-11677
Abstract

An efficient and concise approach for the synthesis of polysubstituted pyridines has been achieved through copper-catalyzed oxidative sp3 C–H coupling of oxime acetates with toluene derivatives. Besides, benzylamine and p-toluenesulfonylhydrazone were also introduced to react with oxime acetates to enrich the diversity of this synthetic method. These transformations provide highly flexible and facile preparation of substituted pyridines and thus are useful in practical synthesis.

Subject Area均相催化 ; 有机化学
DOI10.1021/acs.joc.6b02081
Funding Organizationthe National Natural Science Foundation of China (Nos. 21372102;21403256)
Indexed BySCI
If4.849
Language英语
Funding Project催化新工艺研究组
compositor第二作者单位
Citation statistics
Cited Times:45[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/21003
Collection精细石油化工中间体国家工程研究中心(ERC)
羰基合成与选择氧化国家重点实验室(OSSO)
Corresponding AuthorChen BH(陈保华)
Affiliation1.State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University, Gansu, Lanzhou 730000, People’s Republic of China
2.State Key Laboratory for Oxo Synthesis and Selective Oxidation, Suzhou Research Institute of LICP, Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences, Lanzhou 730000, People’s Republic of China
Recommended Citation
GB/T 7714
Fu YJ,Wang PP,Guo X,et al. Synthesis of Polyfunctional Pyridines via Copper-Catalyzed Oxidative Coupling Reactions[J]. Journal of Organic Chemistry,2016,81(23):11671-11677.
APA Fu YJ.,Wang PP.,Guo X.,Wu P.,Meng X.,...&陈保华.(2016).Synthesis of Polyfunctional Pyridines via Copper-Catalyzed Oxidative Coupling Reactions.Journal of Organic Chemistry,81(23),11671-11677.
MLA Fu YJ,et al."Synthesis of Polyfunctional Pyridines via Copper-Catalyzed Oxidative Coupling Reactions".Journal of Organic Chemistry 81.23(2016):11671-11677.
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