| Expedient Synthesis of Substituted Benzoheterocycles using 2-Butoxy-2,3-dihydrofurans as [4+2] Benzannulation Reagents | |
| Department | OSSO国家重点实验室 |
| Liu, Changhui1; Huang, Wenbo1; Wang, Man1; Pan, Bin1; Gu YL(顾彦龙)1,2; Gu YL(顾彦龙) | |
| 2016 | |
| Source Publication | Advanced Synthesis and Catalysis
 |
| ISSN | 1615-4150 |
| Volume | 358Issue:14Pages:2260-2266 |
| Abstract | 2-Alkoxy-2,3-dihydrofurans were found to be versatile benzannulation reagents. Indoles can be synthesized in good to excellent yields via the [4+2] annulation of 2-butoxy-2,3-dihydrofuran with pyrroles catalyzed by copper bromide. With the same protocol, carbazoles can also be obtained when indoles are used as starting material with the aid of p-toluenesulfonic acid. This type of benzannulation reagent can also be used to synthesize benzofuran, benzothiophene and naphthalene derivatives in the presence of a catalytic amount of triflic acid in moderate yields. This benzannulation protocol features wide substrate scope and mild reaction condition. Moreover, most of examples have a good regioslectivity. |
| Keyword | Benzannulation Benzofurans Carbazoles Copper Dihydrofurans Indoles |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1002/adsc.201600185 |
| Funding Organization | National Natural Science Foundation of China (21373093);the Fundamental Research Funds for the Central Universities of China (2014ZZGH019) |
| Indexed By | SCI |
| If | 5.646 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/20470 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Gu YL(顾彦龙) |
| Affiliation | 1.Huazhong Univ Sci & Technol, Key Lab Mat Chem Energy Convers & Storage, Hubei Key Lab Mat Chem & Serv Failure, Minist Educ,Sch Chem & Chem Engn, Wuhan 430074, Peoples R China 2.Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Liu, Changhui,Huang, Wenbo,Wang, Man,et al. Expedient Synthesis of Substituted Benzoheterocycles using 2-Butoxy-2,3-dihydrofurans as [4+2] Benzannulation Reagents[J]. Advanced Synthesis and Catalysis,2016,358(14):2260-2266. |
| APA | Liu, Changhui,Huang, Wenbo,Wang, Man,Pan, Bin,Gu YL,&顾彦龙.(2016).Expedient Synthesis of Substituted Benzoheterocycles using 2-Butoxy-2,3-dihydrofurans as [4+2] Benzannulation Reagents.Advanced Synthesis and Catalysis,358(14),2260-2266. |
| MLA | Liu, Changhui,et al."Expedient Synthesis of Substituted Benzoheterocycles using 2-Butoxy-2,3-dihydrofurans as [4+2] Benzannulation Reagents".Advanced Synthesis and Catalysis 358.14(2016):2260-2266. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| LZ01029333.pdf（1638KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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