Cycloartane-type triterpenoids from Astragalus hoantchy Franch.
Department中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Guo K(郭凯)1; He XF(何小凤)1; Lu DX(路等学)2; Zhang YP(张艳萍)3; Li XZ(李秀壮)1; Yan ZQ(燕志强)1; Qin B(秦波)1; Qin B(秦波)
2017
Source PublicationNatural Product Research
ISSN1478-6419
Volume31Issue:3Pages:314-319
Abstract

A new cycloartane-type triterpenoid, 3β-acetoxy-9β,19-cyclolanost-24E-ene-1α,16β-diol-27-O-β-d-glucopyranoside (1), together with three known ones (24) were isolated from the aerial parts of Astragalus hoantchy. The structure of compound 1 was elucidated by detailed spectroscopic analyses including 1D and 2D NMR, HRESIMS, and IR experiments. All of the four compounds were isolated from A. hoantchy for the first time. The antifungal activities of compounds 14 against a phytopathogenic fungus (Alternaria solani) were evaluated with the result that compound 3 exhibited a moderate activity with an IC50 value of 284 μg/mL.

KeywordAstragalus Hoantchy Leguminosae Cycloartane Triterpenoid Antifungal Activity
Subject Area分析化学与药物化学
DOI10.1080/14786419.2016.1236100
Funding Organizationthe National Natural Science Foundation of China [grant number 31570354];[grant number 21302195];[grant number 31300290];the Agricultural Biotechnology Research and Development Programme of Gansu Province [grant number GNSW-2015-25];Research and Development Project of New Technology and Equipment of Special Programme in the Field of Agriculture Ecological Environment Protection of Gansu Province;Cooperation Programme to Gansu Province of Lanzhou Branch of the Chinese Academy of Sciences;135 Major Breakthrough Project of the Chinese Academy of Sciences
Indexed BySCI
If1.828
Language英语
Funding Project植物化学生态研究组
compositor第一作者单位
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Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/20390
Collection中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
Corresponding AuthorQin B(秦波)
Affiliation1.Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences
2.Institute of Biology, Gansu Academy of Sciences
3.Fisheries Research Institute of Gansu Province
Recommended Citation
GB/T 7714
Guo K,He XF,Lu DX,et al. Cycloartane-type triterpenoids from Astragalus hoantchy Franch.[J]. Natural Product Research,2017,31(3):314-319.
APA Guo K.,He XF.,Lu DX.,Zhang YP.,Li XZ.,...&秦波.(2017).Cycloartane-type triterpenoids from Astragalus hoantchy Franch..Natural Product Research,31(3),314-319.
MLA Guo K,et al."Cycloartane-type triterpenoids from Astragalus hoantchy Franch.".Natural Product Research 31.3(2017):314-319.
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