Metal-Organic Frameworks/Graphene Oxide Composite: A New Enzymatic Immobilization Carrier for Hydrogen Peroxide Biosensors | |
Department | 固体润滑国家重点实验室 |
Fan ZJ(范增杰)1; Wang JQ(王金清)2; Nie, Yingying3; Ren, Liling1; Liu B(刘斌)1; Liu G(刘刚)2,4; Fan ZJ(范增杰); Liu B(刘斌) | |
2016 | |
Source Publication | Journal of The Electrochemical Society |
ISSN | 0013-4651 |
Volume | 163Issue:3Pages:B32-B37 |
Abstract | Enzymatic loss and inactivation are two main problems that can degrade the performance of biosensor. In order to resolve the problems, a new enzymatic immobilization carrier was developed by using biomimetic methods. Horseradish peroxidase (HRP) was initially encapsulated into zeolitic imidazolate frameworks (ZIFs) severed as protective structure. To overcome electron transfer barrier of ZIFs, graphene oxide (GO) of high conductive graphene precursor was used to enhance their conductivity. Subsequently, ZIFs@HRP/GO and GO-polyethyleneimine with opposite charges were alternatively assembled onto the substrate of indium tin oxide to construct multilayer films of the biosensor. Systematic characterizations showed that ZIF-8 with an average size of approximately 160.9 nm encapsulating HRP uniformly grew onto the surface of GO. The newly designed structure combined with the excellent properties of the GO and ZIFs guarantee easy, direct electrochemistry and good catalytic activity toward H2O2 oxidation can be achieved with this biosensor. Electrochemical experiment study indicate that the resulting biosensor presented a wide linear range of 0.02–6 mmol/L, a low detection limit of 3.4 μmol /L (S/N = 3), excellent anti-interference ability, and long-term stability as well. |
Subject Area | 材料科学与物理化学 |
DOI | 10.1149/2.0531603jes |
Funding Organization | the Natural Science Foundation of China (81571829);the Fundamental Research Funds for Central Universities (lzujbky-2015-35;lzujbky-2015-289;lzujbky-2015-102);the Natural Science Foundation of Gansu Province, China (145RJZA126);the Science and Technology Projects of Gansu Province,China (145RJYA315);Youth Science and Technology Innovation Foundation of Gansu Academy of Sciences, China (2013 QN-02) |
Indexed By | SCI |
If | 3.259 |
Language | 英语 |
Funding Project | 聚合物摩擦学组 |
compositor | 第二作者单位 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.licp.cn/handle/362003/19745 |
Collection | 固体润滑国家重点实验室(LSL) |
Corresponding Author | Fan ZJ(范增杰); Liu B(刘斌) |
Affiliation | 1.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China 3.Gansu Acad Sci, Inst Sensing Technol, Lanzhou 730000, Peoples R China 4.Lanzhou Univ, Sch Informat Sci & Engn, Lanzhou 730000, Peoples R China |
Recommended Citation GB/T 7714 | Fan ZJ,Wang JQ,Nie, Yingying,et al. Metal-Organic Frameworks/Graphene Oxide Composite: A New Enzymatic Immobilization Carrier for Hydrogen Peroxide Biosensors[J]. Journal of The Electrochemical Society,2016,163(3):B32-B37. |
APA | Fan ZJ.,Wang JQ.,Nie, Yingying.,Ren, Liling.,Liu B.,...&刘斌.(2016).Metal-Organic Frameworks/Graphene Oxide Composite: A New Enzymatic Immobilization Carrier for Hydrogen Peroxide Biosensors.Journal of The Electrochemical Society,163(3),B32-B37. |
MLA | Fan ZJ,et al."Metal-Organic Frameworks/Graphene Oxide Composite: A New Enzymatic Immobilization Carrier for Hydrogen Peroxide Biosensors".Journal of The Electrochemical Society 163.3(2016):B32-B37. |
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LZ01028716.pdf(452KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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