| Synthesis of Resins with Ionic Liquids for Purification of Flavonoids from Hippophae rhamnoides L. Leaves | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Lou S(娄嵩)1,2; Di DL(邸多隆)1,3 ; Di DL(邸多隆)
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| 2012 | |
| Source Publication | Journal of Agricultural and Food Chemistry
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| ISSN | 0021-8561 |
| Volume | 60Issue:26Pages:6546-6558 |
| Abstract | The efficient purification method of high-purity flavonoids from Hippophae rhamnoides L. (sea buckthorn) is reported. A novel room temperature ionic liquid-based macroporous adsorption resin (MAR), N-methylimidazole/MARs (Mim/MARs), was prepared on the basis of the Friedel–Crafts-catalyzed and surface-modified technique. The material exhibited favorable characteristics for adsorption application, including high pore volume (1.90 cm3/g, 3 times as big as the optimal commercial adsorbent), good pore structure (type IV isotherm with an H1 hysteresis loop, the most favorable structure for adsorption purposes), narrow particle size and pore size distribution (1.2 mm with a standard deviation of 0.106 mm), and excellent chemical stability. This paper also presents the first experimental evidence that the functional groups of the modified materials and composite action of certain molecular interactions between the adsorbent and flavonoids affected the adsorption process. Moreover, a new sphere-size adsorption kinetics model in which the adsorption process contained three or more compartments and detailed parameters of sphere size was developed according to the multicompartment kinetics model and Karichhoff’s theory by investigating the regression of the experimental results. The conclusion that the first compartment of the adsorption process onto Mim/MARs mainly occurred on spheres larger than 0.83 mm and the second and third ones mainly occurred on spheres of 0.46–0.83 and 0.22–0.46 mm, respectively, was drawn from this new sphere-size adsorption kinetics model. |
| Keyword | Ionic Liquids Macroporous Adsorption Resins Separation Flavonoids Hippophae Rhamnoides L. L.aves |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1021/jf300633g |
| Funding Organization | the Hundred Talents Program of the Chinese Academy of Sciences (CAS);the National Natural Sciences Foundation of China (NSFC, no. 20974116) |
| Indexed By | SCI |
| If | 2.906 |
| Language | 英语 |
| Funding Project | 药物工艺标准研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19562 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Di DL(邸多隆) |
| Affiliation | 1.Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China 2.Graduate University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China 3.Centre of Resource Chemical and New Material, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Qingdao 266100, People's Republic of China |
| Recommended Citation GB/T 7714 | Lou S,Di DL,Di DL. Synthesis of Resins with Ionic Liquids for Purification of Flavonoids from Hippophae rhamnoides L. Leaves[J]. Journal of Agricultural and Food Chemistry,2012,60(26):6546-6558. |
| APA | Lou S,Di DL,&邸多隆.(2012).Synthesis of Resins with Ionic Liquids for Purification of Flavonoids from Hippophae rhamnoides L. Leaves.Journal of Agricultural and Food Chemistry,60(26),6546-6558. |
| MLA | Lou S,et al."Synthesis of Resins with Ionic Liquids for Purification of Flavonoids from Hippophae rhamnoides L. Leaves".Journal of Agricultural and Food Chemistry 60.26(2012):6546-6558. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| jf300633g.pdf（1874KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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