| Palladium(II)-Catalyzed Tandem Cyclization/C-H Functionalization of Alkynes for the Synthesis of Functionalized Indoles | |
| Department | 固体润滑国家重点实验室 |
| Xia XF(夏晓峰)1; Wang, Ning1; Zhang, Lu-Lu1; Song XR(宋贤荣)1; Liu XY(刘雪原)1; Liang YM(梁永民)1,2; Liang YM(梁永民) | |
| 2012 | |
| Source Publication | Journal of Organic Chemistry
 |
| ISSN | 0022-3263 |
| Volume | 77Issue:20Pages:9163-9170 |
| Abstract | A palladium-catalyzed tandem cyclization/C–H functionalization of two alkynes was accomplished to construct a series of polycyclic functionalized indoles. A range of internal alkynes bearing synthetically useful functional groups were tolerated. A good regioselectivity was observed when alkyl-substituted alkynes were introduced into the reaction system, and a single product was obtained. Molecular oxygen was used as the terminal oxidant in the approach, rendering the reaction more sustainable. |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1021/jo301741j |
| Funding Organization | the National Science Foundation (NSF 21072080);the Fundamental Research Funds for the Central Universities (lzujbky-2011-151;lzujbky-2010-k09);National Basic Research Program of China (973 Program) 2010CB833203;"111" program of MOE;the program for Changjiang Scholars and Innovative Research Team in University (IRT1138) |
| Indexed By | SCI |
| If | 4.564 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19500 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liang YM(梁永民) |
| Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Xia XF,Wang, Ning,Zhang, Lu-Lu,et al. Palladium(II)-Catalyzed Tandem Cyclization/C-H Functionalization of Alkynes for the Synthesis of Functionalized Indoles[J]. Journal of Organic Chemistry,2012,77(20):9163-9170. |
| APA | Xia XF.,Wang, Ning.,Zhang, Lu-Lu.,Song XR.,Liu XY.,...&梁永民.(2012).Palladium(II)-Catalyzed Tandem Cyclization/C-H Functionalization of Alkynes for the Synthesis of Functionalized Indoles.Journal of Organic Chemistry,77(20),9163-9170. |
| MLA | Xia XF,et al."Palladium(II)-Catalyzed Tandem Cyclization/C-H Functionalization of Alkynes for the Synthesis of Functionalized Indoles".Journal of Organic Chemistry 77.20(2012):9163-9170. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| jo301741j.pdf（677KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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