| Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon nanotubes for the determination of aconitines in human serum samples | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Zhang HF(张洪飞)1,2,3; Shi YP(师彦平)1,2 ; Shi YP(师彦平)
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| 2012 | |
| Source Publication | Analytica Chimica Acta
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| ISSN | 0003-2670 |
| Volume | 724Pages:54-60 |
| Abstract | A magnetic carbon nanomaterial for Fe3O4 enclosure hydroxylated multi-walled carbon nanotubes (Fe3O4-EC-MWCNTs-OH) was prepared by the aggregating effect of Fe3O4 nanoparticle on MWCNTs-OH, and combined with high-performance liquid chromatography (HPLC)/diode array detection (DAD) to determine the aconitines (aconitine, hypaconitine and mesaconitine) in human serum samples. Compared with other extraction modes investigated in experiment, Fe3O4-EC-MWCNTs-OH sorbents showed a good affinity to target analytes. Some important parameters that could influence extraction efficiency of aconitines, including the extraction mode, amounts of Fe3O4-EC-MWCNTs-OH, pH of sample solution, extraction time, desorption solvent and desorption time, were optimized. Under optimal conditions, the recoveries of spiked serum samples were between 98.0% and 103.0%; relative standard deviations (RSDs) ranged from 0.9% to 6.2%. The correlation coefficients varied from 0.9996 to 0.9998. The limits of detection ranged from 3.1 ng mL−1 to 4.1 ng mL−1 at a signal-to-noise ratio of 3. The experimental results showed that the proposed method was feasible for the analysis of aconitines in serum samples. |
| Keyword | Fe3o4 Nanoparticles Hydroxylated Multi-walled Carbon Nanotubes Aconitines Serum Samples |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1016/j.aca.2012.02.039 |
| Funding Organization | the National Natural Science Foundation of China (no. 21075127;20875095) |
| Indexed By | SCI |
| If | 4.387 |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19444 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang HF,Shi YP,Shi YP. Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon nanotubes for the determination of aconitines in human serum samples[J]. Analytica Chimica Acta,2012,724:54-60. |
| APA | Zhang HF,Shi YP,&师彦平.(2012).Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon nanotubes for the determination of aconitines in human serum samples.Analytica Chimica Acta,724,54-60. |
| MLA | Zhang HF,et al."Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon nanotubes for the determination of aconitines in human serum samples".Analytica Chimica Acta 724(2012):54-60. |
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| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S000326701200（1260KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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