| Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral alpha-branched heteroaryl amines | |
| Department | OSSO国家重点实验室 |
| Zhang, Jinlong1,2; Yang, Yuhong1,2; Wang, Mei1,2; Lin, Li1,2; Wang R(王锐)1,2,3; Wang R(王锐) | |
| 2012 | |
| Source Publication | Tetrahedron Letters
 |
| ISSN | 0040-4039 |
| Volume | 53Issue:51Pages:6893-6896 |
| Abstract | This work concerns the asymmetric additions of benzothiazole to a variety of N-tert-butanesulfinyl imines with excellent diastereoselectivities (d.r. up to >99:1). Amino alkoxyl lithium was the key additive to obtain the excellent diastereoselectivity. More functionalized 4-methyl-5-vinyl thiazole and alkyl imines which can isomerize to enamines are also compatible substrates to the present protocol. |
| Keyword | Asymmetric Synthesis Benzothiazole Diarylmethylamine Diastereoselectivity N-tert-butanesulfinyl Imine |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1016/j.tetlet.2012.09.131 |
| Funding Organization | NSFC (nos. 21002043;21272107;20932003);the National S&T Major Project of China (2012ZX09504-001-003);Fundamental Research Funds for the Central Universities (lzujbky-2010-184) |
| Indexed By | SCI |
| If | 2.397 |
| Language | 英语 |
| compositor | 第三作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19432 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Lin, Li; Wang R(王锐) |
| Affiliation | 1.Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Inst Biochem & Mol Biol, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Jinlong,Yang, Yuhong,Wang, Mei,et al. Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral alpha-branched heteroaryl amines[J]. Tetrahedron Letters,2012,53(51):6893-6896. |
| APA | Zhang, Jinlong,Yang, Yuhong,Wang, Mei,Lin, Li,Wang R,&王锐.(2012).Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral alpha-branched heteroaryl amines.Tetrahedron Letters,53(51),6893-6896. |
| MLA | Zhang, Jinlong,et al."Asymmetric addition of benzothiazole to N-tert-butanesulfinyl imine for the synthesis of chiral alpha-branched heteroaryl amines".Tetrahedron Letters 53.51(2012):6893-6896. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S004040391201（573KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment