| Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Yang JL(杨军丽)1 ; Shi YP(师彦平)1,2,3; Shi YP(师彦平)
| |
| 2012 | |
| Source Publication | Phytochemistry
 |
| ISSN | 0031-9422 |
| Volume | 76Pages:124-132 |
| Abstract | Cycloartane-type triterpenoids (1-3), seven sesquiterpenoids (7-13), and five previously reported secondary metabolites, including three cycloartane-type triterpenoids (4-6) and two sesquiterpenoids (14 and 15), were isolated from the resinous exudates of Commiphora opobalsamum. Their structures were elucidated by extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with literature data. The structures of 1, 3, and 7 were confirmed by single-crystal X-ray diffraction analysis. The absolute configuration of 1 was interpreted by the incorporation of CHCl3 (crystallization solvent) in the crystal and that of 10 was determined by the CD exciton chirality method. Compound 12 represents the first example of a 12-norcadinane-type sesquiterpenoid. Furthermore, compounds 1,3,7, and 10-14 were evaluated for cytotoxicity against HeLa and HepG2 cell lines. |
| Keyword | Commiphora Opobalsamum Burseraceae Cycloartane-type Triterpenoids Sesquiterpenoids Cytotoxicity Single-crystal X-ray Diffraction Cd Exciton Chirality |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1016/j.phytochem.2012.01.004 |
| Funding Organization | the Foundation for the National Natural Science Foundation of China (Nos. 20621091;20875095;21075127) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物化学成分研究组 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19352 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shi YP(师彦平) |
| Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Key Lab Nat Med Gansu Prov, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Yang JL,Shi YP,Shi YP. Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum[J]. Phytochemistry,2012,76:124-132. |
| APA | Yang JL,Shi YP,&师彦平.(2012).Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum.Phytochemistry,76,124-132. |
| MLA | Yang JL,et al."Cycloartane-type triterpenoids and sesquiterpenoids from the resinous exudates of Commiphora opobalsamum".Phytochemistry 76(2012):124-132. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S003194221200（532KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment