| Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Feng ZF(冯祖飞)1,2,3; Sun XM(孙小明)1,2,3 ; Ning, Sheng-rong4; Di DL(邸多隆)1,2,4; Di DL(邸多隆)
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| 2012 | |
| Source Publication | Current Pharmaceutical Analysis
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| ISSN | 1573-4129 |
| Volume | 8Issue:3Pages:225-235 |
| Abstract | High-performance liquid chromatography (HPLC) was employed in a fingerprint analysis of Radix astragali. A characteristic HPLC profile of known Radix astragali samples collected from five primary habitats in China was established by evaluating 15 samples with chemometric methods, including similarity evaluation, hierarchical cluster analysis (HCA), principal component analysis (PCA) and discriminant analysis (DA). The feasibility and advantages of employing chromatographic fingerprinting combined with chemometric methods were investigated and demonstrated in the evaluation of Radix astragali for the first time. The results showed that the chromatographic fingerprint combined with chemometric methods could efficiently distinguish Radix astragali from various areas and provide quality control in the quantitative analysis. |
| Keyword | Chemometric Fingerprint Hplc Radix Astragali |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Science and Technology Support Programme (No. 2007BAI37B05);the "Hundred Talents Program" of the Chineae Academy of Sciences (CAS) |
| Indexed By | SCI |
| If | 1.333 |
| Language | 英语 |
| Funding Project | 药物工艺标准研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19336 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Di DL(邸多隆) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Lanzhou Univ, Pharmacol Sch, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Feng ZF,Sun XM,Ning, Sheng-rong,et al. Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods[J]. Current Pharmaceutical Analysis,2012,8(3):225-235. |
| APA | Feng ZF,Sun XM,Ning, Sheng-rong,Di DL,&邸多隆.(2012).Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods.Current Pharmaceutical Analysis,8(3),225-235. |
| MLA | Feng ZF,et al."Quality Control of Fingerprint of Radix Astragali by High-Performance Liquid Chromatography Coupled with Chemometric Methods".Current Pharmaceutical Analysis 8.3(2012):225-235. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| LZ01028419.pdf（1089KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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