| Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes | |
| Department | 固体润滑国家重点实验室 |
| He, Yu-Tao1; Li, Lian-Hua1; Zhou, Zhao-Zhao1; Hua, Hui-Liang1; Qiu, Yi-Feng1; Liu, Xue-Yuan1; Liang YM(梁永民)1,2; Liang YM(梁永民) | |
| 2014 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 16Issue:15Pages:3896-3899 |
| Abstract | A novel three-component strategy for the cyanotrifluoromethylation/azidotrifluoromethylation and carbocyclization of 1,6-enynes is developed. The reaction proceeds smoothly under a moderate temperature by using a copper catalyst, which provides a rapid and concise access to addition–carbocyclization products. Furthermore, the products obtained can be useful building blocks in discoveries of lead compounds and other biologically active CF3-containing heterocycles. |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1021/ol501574f |
| Funding Organization | the National Natural Science Foundation (NSF 21272101;201302076);the National Basic Research Program of China (973 Program) 2010CB-33203;the Fundamental Researxh Funds for the Central Universities (lzujbhy-2014-243;lzujbky-2014-194);the "111" Project;Program for Changjiang Scholars and Innovative Research Team in University (IRT1138) |
| Indexed By | SCI |
| If | 6.364 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19250 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liang YM(梁永民) |
| Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | He, Yu-Tao,Li, Lian-Hua,Zhou, Zhao-Zhao,et al. Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes[J]. Organic Letters,2014,16(15):3896-3899. |
| APA | He, Yu-Tao.,Li, Lian-Hua.,Zhou, Zhao-Zhao.,Hua, Hui-Liang.,Qiu, Yi-Feng.,...&梁永民.(2014).Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes.Organic Letters,16(15),3896-3899. |
| MLA | He, Yu-Tao,et al."Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes".Organic Letters 16.15(2014):3896-3899. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| ol501574f.pdf（930KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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