| Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy | |
| Department | 固体润滑国家重点实验室 |
Lin, Bingpeng1; Zhong, Mei1; Zheng, Chengdong1; Cao, Lin1; Wang, Dengli1; Wang, Lina1; Liang J(梁军)2 ; Cao, Baocheng1
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| 2015 | |
| Source Publication | Surface and Coatings Technology
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| ISSN | 0257-8972 |
| Volume | 281Pages:82-88 |
| Abstract | Mg alloys have great potential in biodegradable orthopedic implant applications owing to their rapid degradation in physiological environments and mechanical properties similar to those of bone. However, the extremely high corrosion rate of magnesium alloys has also restricted their medical applications. In this work, a hydroxyapatite (HA) coating was prepared by polydopamine (PDA) induced biomimetic mineralization in a CaP solution to improve the in vitro corrosion resistance and biocompatibility of the AZ31 Mg alloy. The evolution of the phase structure, chemical composition, and surface morphology of the modified AZ31 Mg alloy substrate was evaluated by scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. Potentiodynamic polarization and hydrogen evolution tests demonstrated that the corrosion resistance of the modified AZ31 Mg alloy significantly increased compared with that of the pristine sample. Cytotoxicity testing and cell morphology analysis showed that the as-modified alloy did not induce toxic effects, and promoted the proliferation of L-929 cells. The results suggest that the dopamine-induced biomimetic apatite coating approach is of significant value in the development of biodegradable Mg alloy implants. |
| Keyword | Biomimetic Coating Polydopamine Corrosion Resistance Magnesium Alloy Cytotoxicity Hydroxyapatite |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1016/j.surfcoat.2015.09.033 |
| Funding Organization | the Natural Science Foundation of Gansu Province, China (grant no. 1208RJZA236) |
| Indexed By | SCI |
| If | 2.139 |
| Language | 英语 |
| Funding Project | 空间润滑材料组 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19149 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Cao, Baocheng |
| Affiliation | 1.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | Lin, Bingpeng,Zhong, Mei,Zheng, Chengdong,et al. Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy[J]. Surface and Coatings Technology,2015,281:82-88. |
| APA | Lin, Bingpeng.,Zhong, Mei.,Zheng, Chengdong.,Cao, Lin.,Wang, Dengli.,...&Cao, Baocheng.(2015).Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy.Surface and Coatings Technology,281,82-88. |
| MLA | Lin, Bingpeng,et al."Preparation and characterization of dopamine-induced biomimetic hydroxyapatite coatings on the AZ31 magnesium alloy".Surface and Coatings Technology 281(2015):82-88. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S025789721530（1486KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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