| Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes | |
| Department | 固体润滑国家重点实验室 |
| He, Yu-Tao1; Wang, Qiang1; Zhao, Jiahui1; Wang, Xiao-Zhen1; Qiu, Yi-Feng1; Yang, Yu-Chen1; Hu, Jing-Yuan1; Liu XY(刘雪原)1; Liang YM(梁永民)1,2; Liang YM(梁永民) | |
| 2015 | |
| Source Publication | Advanced Synthesis and Catalysis
 |
| ISSN | 1615-4150 |
| Volume | 357Issue:14-15Pages:3069-3075 |
| Abstract | A method for the synthesis of trifluoromethyl CF3-substituted spirocyclic compounds containing with a unique quaternary carbon center from readily available starting materials has been developed. The reaction provides a facile access to 2H-azirines via cascade cyclization. These compounds constitute a new class of functionalized synthetic intermediates, which can be used for the synthesis of various nitrogen-containing heterocycles and biologically active CF3-containing compounds. |
| Keyword | 2h-azirines Cascade Cyclization Copper Enynes Spirocyclic Skeleton |
| Subject Area | 材料科学与物理化学 |
| DOI | 10.1002/adsc.201500510 |
| Funding Organization | the National Natural Science Foundation (NSF 21272101;21472074;21472073);the Fundamental Research Funds for Central Universities (lzujbky-2014-243);the "111" Project (J1103307);Program for Changjiang Scholars and Innovative Research Team in University (IRT1138);the Cuiying Student Innovation Fund of Lanzhou University (CYCXJJ-2015003) |
| Indexed By | SCI |
| If | 6.453 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/19061 |
| Collection | 固体润滑国家重点实验室（LSL） |
| Corresponding Author | Liang YM(梁永民) |
| Affiliation | 1.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China |
| Recommended Citation GB/T 7714 | He, Yu-Tao,Wang, Qiang,Zhao, Jiahui,et al. Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes[J]. Advanced Synthesis and Catalysis,2015,357(14-15):3069-3075. |
| APA | He, Yu-Tao.,Wang, Qiang.,Zhao, Jiahui.,Wang, Xiao-Zhen.,Qiu, Yi-Feng.,...&梁永民.(2015).Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes.Advanced Synthesis and Catalysis,357(14-15),3069-3075. |
| MLA | He, Yu-Tao,et al."Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes".Advanced Synthesis and Catalysis 357.14-15(2015):3069-3075. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| LZ01028474.pdf（875KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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