| Surface modification of polytetrafluoroethylene column for two-stationary phase separations by counter-current chromatography | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
Quan KJ(全凯军)1,2,3 ; Huang XY(黄新异)1,2; Li XT(李晓婷)1,2,3; Wang GH(王高红)1,2,3; Liu YJ(刘言娟)1,2,3; Duan WD(段文达)1,2,3; Di DL(邸多隆)1,2; Di DL(邸多隆)
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| 2015 | |
| Source Publication | Journal of Chromatography A
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| ISSN | 0021-9673 |
| Volume | 1422Pages:155-162 |
| Abstract | To improve the separation capability of CCC, a novel solid-liquid two-stationary phases CCC (ASP-CCC) column was prepared employing graphene oxide (GO) conjugated poly-dopamine (PD) coating (GO/PD) as auxiliary stationary phase (ASP). The results of Scanning electron microscopy (SEM), contact angle and X-ray photoelectron spectroscopy (XPS) indicated that nanostructured GO and PD were successfully grafted on the inner wall of the PTFE column. Three alkaloid compounds were selected as the target analytes to evaluate the performance of the novel column. Because of the intermolecular force (hydrogen bond, electrostatic interaction and pi-pi interaction) between the ASP and model compounds, three analytes were well separated with this novel ASP-CCC column. Additionally, the novel column exhibited higher stationary phase retention ratio, about 8%, than original column without changing the chromatographic condition. Furthermore, the eluotropic sequence of analytes on novel column was in accordance with that in the original column. This suggested that the novel column is a CCC column with auxiliary stationary phase (ASP) in its own right, and the present separation mode is the combination of partition chromatography and adsorption chromatography. |
| Keyword | Ccc Poly-dopamine Auxiliary Stationary Phase Adsorption Graphene Oxide Alkaloid |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1016/j.chroma.2015.10.009 |
| Funding Organization | the National Scientific Foundation of China (NSFC no. 21175142);Open Fund of Key Laboratory of Chemistry of Northwestern Plant Resources of The Chinese Academy of Science (no. CNPR-2011kfkt-02) |
| Indexed By | SCI |
| If | 4.169 |
| Language | 英语 |
| Funding Project | 药物工艺标准研究组 |
| compositor | 第一作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18696 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Di DL(邸多隆) |
| Affiliation | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | KJ Quan, XY Huang, XT Li, GH Wang, YJ Liu, WD Duan, DL Di. Surface modification of polytetrafluoroethylene column for two-stationary phase separations by counter-current chromatography[J]. Journal of Chromatography A,2015,1422:155-162. |
| APA | Quan KJ.,Huang XY.,Li XT.,Wang GH.,Liu YJ.,...&邸多隆.(2015).Surface modification of polytetrafluoroethylene column for two-stationary phase separations by counter-current chromatography.Journal of Chromatography A,1422,155-162. |
| MLA | Quan KJ,et al."Surface modification of polytetrafluoroethylene column for two-stationary phase separations by counter-current chromatography".Journal of Chromatography A 1422(2015):155-162. |
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| Surface modification（1833KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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