| Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes | |
| Department | OSSO国家重点实验室 |
| Zhu, Yuanyuan1; Li, Xiaoyuan1; Chen, Qiao1; Su, Jinhuan1; Jia, Fengjing1; Qiu, Shuai1; Ma, Mingxia1; Sun, Quantao1; Yan, Wenjin1; Wang, Kairong1; Wang R(王锐)1,2,3; Wang R(王锐) | |
| 2015 | |
| Source Publication | Organic Letters
 |
| ISSN | 1523-7060 |
| Volume | 17Issue:15Pages:3826-3829 |
| Abstract | A catalytic asymmetric method for the synthesis of 2-CF3 chromanes has been described. Generally, the squaramide-catalyzed cascade reaction of 2-hydroxychalcones with β-CF3-nitroalkenes gave the CF3-containing heterocyclic compounds bearing three contiguous stereogenic centers in excellent yields, diastereoselectivities, and enantioselectivities. |
| Subject Area | 物理化学与绿色催化 |
| DOI | 10.1021/acs.orglett.5b01799 |
| Funding Organization | the National Natural Science Foundation of China (Nos. 21432003;21272108;31200584;91213302);the Fundamental Research Funds for the Central Universities (lzujbky-2015-155);the Research Fund for the Doctoral Program of Higher Education of China (20120211120045);the Key National S&T Program “Major New Drug Development” of the Ministry of Science and Technology of China (2012ZX09504001-003) |
| Indexed By | SCI |
| If | 6.732 |
| Language | 英语 |
| compositor | 第二作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18549 |
| Collection | 羰基合成与选择氧化国家重点实验室（OSSO） |
| Corresponding Author | Yan, Wenjin; Wang, Kairong; Wang R(王锐) |
| Affiliation | 1.Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China |
| Recommended Citation GB/T 7714 | Zhu, Yuanyuan,Li, Xiaoyuan,Chen, Qiao,et al. Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes[J]. Organic Letters,2015,17(15):3826-3829. |
| APA | Zhu, Yuanyuan.,Li, Xiaoyuan.,Chen, Qiao.,Su, Jinhuan.,Jia, Fengjing.,...&王锐.(2015).Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes.Organic Letters,17(15),3826-3829. |
| MLA | Zhu, Yuanyuan,et al."Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes".Organic Letters 17.15(2015):3826-3829. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| acs.orglett.5b01799.（808KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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