| Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging | |
| Department | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Liu, Meiying1; Zhang, Xiqi2; Yang, Bin2; Li Z(李湛)3; Deng, Fengjie1; Yang, Yang1; Zhang, Xiaoyong1,2; Wei, Yen2 | |
| 2015 | |
| Source Publication | Carbohydrate Polymers
 |
| ISSN | 0144-8617 |
| Volume | 121Pages:49-55 |
| Abstract | Fluorescent organic nanoparticles (FONs) based on carbohydrate polymers were prepared through one-pot hydrothermal treatment of starch in the presence of polyethyleneimine. These FONs (named as PEI-Starch FONs) were characterized by a series of techniques including UV–Vis absorption spectroscopy, fluorescent spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy and X-ray photoelectron spectroscopy. Results showed that the size of PEI-Starch FONs is 10–30 nm. The PEI-Starch FONs exhibited high water dispersibility because of the existence of hydrophilic functional groups on their surface. After excited with different wavelength, PEI-Starch FONs emitted strong and excitation-dependent fluorescence. To evaluate their potential for biomedical applications, biocompatibility and cell uptake behavior of PEI-Starch FONs were further investigated. We demonstrated that PEI-Starch FONs are biocompatible with cells and can be easily internalized by cells within 3 h. Taken together, novel FONs have been prepared via a simple and scalable hydrothermal method using starch and polyethyleneimine as precursors. These PEI-Starch FONs showed excellent fluorescence properties, high water dispersibility and good biocompatibility, making them highly potential for various biomedical applications. |
| Keyword | Starch Polyethyleneimine Fluorescent Organic Nanoparticles Cell Imaging Biomedical Applications |
| Subject Area | 分析化学与药物化学 |
| DOI | 10.1016/j.carbpol.2014.12.047 |
| Funding Organization | the National Natural Science Foundation of China (Nos. 21134004;21201108;51363016);the National 973 Project (No. 2011CB935700) |
| Indexed By | SCI |
| If | 4.219 |
| Language | 英语 |
| Funding Project | 药物分离材料研究组 |
| compositor | 第三作者单位 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/18366 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Zhang, Xiaoyong; Wei, Yen |
| Affiliation | 1.Department of Chemistry/Institute of Polymers, Nanchang University, 999 Xuefu Avenue, Nanchang 330031, China 2.Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, China 3.Key Laboratory of Chemistry of Northwestern Plant Resources, Key Laboratory for Natural Medicine of Gansu Province, Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China |
| Recommended Citation GB/T 7714 | Liu, Meiying,Zhang, Xiqi,Yang, Bin,et al. Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging[J]. Carbohydrate Polymers,2015,121:49-55. |
| APA | Liu, Meiying.,Zhang, Xiqi.,Yang, Bin.,Li Z.,Deng, Fengjie.,...&Wei, Yen.(2015).Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging.Carbohydrate Polymers,121,49-55. |
| MLA | Liu, Meiying,et al."Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging".Carbohydrate Polymers 121(2015):49-55. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 201549-55.pdf（2321KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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