The mineral component of human cardiovascular deposits: morphological, structural and crystal-chemical characterization
Department先进润滑与防护材料研究发展中心
Danilchenko, S. N.1; Kuznetsov, V. N.1; Stanislavov, A. S.1; Kalinkevich, A. N.1; Starikov, V. V.2; Moskalenko, R. A.3; Kalinichenko, T. G.1; Kochenko, A. V.1; Lv JJ(吕晋军)4; Shang J(商剑)4; Yang SR(杨生荣)4
The second department固体润滑国家重点实验室
2013
Source PublicationCrystal Research and Technology
ISSN1521-4079
Volume48Issue:3Pages:153-162
AbstractComplementary experimental techniques were applied to characterize bioapatite nanocrystals from pathological cardiovascular deposits. The investigated collection included the leaflets from aortic valve, leaflets from mitral valve, leaflets from tricuspid valve and calcified aorta's wall. XRD, EDX and FTIR data have shown that all studied samples consist of imperfect apatite with different crystallinity and variable chemical composition. In accordance with TEM data, the crystals of pathological calcified deposits frequently have oblong or rod-like shape (length of 60-90 nanometers, width of 20-30 nanometers). At the same time, in the SEM and TEM experiments, the complex spheroid assemblies and planar sheet-like shaped formations with crystal structure close to apatite were observed. Probably, the different shape and morphology of the particles are caused by different ways of crystal nucleation and growth, although the exact mechanisms remain an open question.
KeywordBioapatite Nanocrystal Cardiovascular Calcification Phase Content Crystallinity Morphology
Subject Area材料科学与物理化学
DOI10.1002/crat.201200443
Funding Organizationthe Ukrainian State Agency for science, innovation and informatization (Grant No 0112U003619);Chinese Academy of Sciences within the bilateral project “Formation mechanism and structural properties of apatite crystals with specific morphology duiing pathological mineralization process”
Indexed BySCI
If1.164
Language英语
Funding Project金属基高温润滑材料组;聚合物摩擦学组
compositor第四作者单位
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.licp.cn/handle/362003/18204
Collection中国科学院材料磨损与防护重点实验室/先进润滑与防护材料研究发展中心
固体润滑国家重点实验室(LSL)
Affiliation1.NAS Ukraine, Inst Appl Phys, Sumy, Ukraine
2.Natl Tech Univ, Kharkov Polytech Inst, Kharkov, Ukraine
3.Sumy State Univ, Inst Med, Sumy, Ukraine
4.Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China
Recommended Citation
GB/T 7714
Danilchenko, S. N.,Kuznetsov, V. N.,Stanislavov, A. S.,et al. The mineral component of human cardiovascular deposits: morphological, structural and crystal-chemical characterization[J]. Crystal Research and Technology,2013,48(3):153-162.
APA Danilchenko, S. N..,Kuznetsov, V. N..,Stanislavov, A. S..,Kalinkevich, A. N..,Starikov, V. V..,...&Yang SR.(2013).The mineral component of human cardiovascular deposits: morphological, structural and crystal-chemical characterization.Crystal Research and Technology,48(3),153-162.
MLA Danilchenko, S. N.,et al."The mineral component of human cardiovascular deposits: morphological, structural and crystal-chemical characterization".Crystal Research and Technology 48.3(2013):153-162.
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