| Simple indole-based colorimetric sensors with electron-withdrawing chromophores: tuning selectivity in anion sensing | |
| Department | 甘肃省天然药物重点实验室 |
Lv YJ(吕永军); Guo Y(郭勇) ; Xu J(徐健); Shao SJ(邵士俊)
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| 2011 | |
| Source Publication | Journal of Fluorine Chemistry
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| ISSN | 0022-1139 |
| Volume | 132Pages:973-977 |
| Abstract | Three simple colorimetric anion sensors (1, 2, and 3) containing anthrone, 1,3-indanedione, and malononitrile as signaling chromophores and an indole binding site have been designed and synthesized. The introduction of electron-withdrawing groups can not only provide chromogenic signal output, but also tune the sensitivity and selectivity of indole-based anion sensors by electron push–pull features. Their anion binding and sensing properties were investigated in detail by dramatic color changes, UV–vis absorption, and 1H NMR. As results revealed, sensor 1 showed high selectivity for F- over AcO- and H2PO4- with a distinct change in color due to the deprotonation of indole NH group. The excellent selectivity of 1 for F- can be attributed to the fitness in the acidity of its NH-group, which is tuned to be able to distinguish the subtle difference in the affinity of F-, AcO-, and H2PO4- to NH proton. |
| Keyword | Anion Binding Indole Chromogenic Sensor Deprotonation Spectroscopy |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | the National Natural Science Foundation of China (Grant No. 20972170 to S-J. Shao);the Natural Science Foundation of Gansu province (No. 096RJ2A033 to Y. Guo) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物分子识别研究组 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1607 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Guo Y(郭勇); Shao SJ(邵士俊) |
| Recommended Citation GB/T 7714 | Lv YJ,Guo Y,Xu J,et al. Simple indole-based colorimetric sensors with electron-withdrawing chromophores: tuning selectivity in anion sensing[J]. Journal of Fluorine Chemistry,2011,132:973-977. |
| APA | 吕永军,郭勇,徐健,&邵士俊.(2011).Simple indole-based colorimetric sensors with electron-withdrawing chromophores: tuning selectivity in anion sensing.Journal of Fluorine Chemistry,132,973-977. |
| MLA | 吕永军,et al."Simple indole-based colorimetric sensors with electron-withdrawing chromophores: tuning selectivity in anion sensing".Journal of Fluorine Chemistry 132(2011):973-977. |
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| Simple indole-based （946KB） | 开放获取 | License | View Application Full Text | |||
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