| Electrocatalytic oxidation and simultaneous determination of uric acid and ascorbic acid on the gold nanoparticles-modified glassy carbon electrode | |
| Department | 甘肃省天然药物重点实验室 |
Hu GZ(胡广志); Ma YG(马永根) ; Guo Y(郭勇); Shao SJ(邵士俊)
| |
| 2008 | |
| Source Publication | Electrochimica Acta
 |
| ISSN | 0013-4686 |
| Volume | 53Pages:6610-6615 |
| Abstract | A new gold nanoparticles-modified electrode (GNP/LC/GCE) was fabricated by self-assembling gold nanoparticles to the surface of the l-cysteine-modified glassy carbon electrode. The modified electrode showed an excellent character for electrocatalytic oxidization of uric acid (UA) and ascorbic acid (AA) with a 0.306V separation of both peaks, while the bare GC electrode only gave an overlapped and broad oxidation peak. The anodic currents of UA and AA on the modified electrode were 6- and 2.5-fold to that of the bare GCE, respectively. Using differential pulse voltammetry (DPV), a highly selective and simultaneous determination of UA and AA has been explored at the modified electrode. DPV peak currents of UA and AA increased linearly with their concentration at the range of 6.0×10−7 to 8.5×10−4 mol L−1 and 8.0×10−6 to 5.5×10−3 mol L−1, respectively. The proposed method was applied for the detection of UA and AA in human urine with satisfactory result. |
| Keyword | Gold Nanoparticles Self-assembled Electrode Uric Acid Ascorbic Acid Simultaneous Determination Differential Pulse Voltammetry |
| Subject Area | 分析化学与药物化学 |
| Funding Organization | National Nature Science Foundation of China (No. 20672121) |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | 药物分子识别研究组 |
| Document Type | 期刊论文 |
| Identifier | http://ir.licp.cn/handle/362003/1393 |
| Collection | 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| Corresponding Author | Shao SJ(邵士俊) |
| Recommended Citation GB/T 7714 | Hu GZ,Ma YG,Guo Y,et al. Electrocatalytic oxidation and simultaneous determination of uric acid and ascorbic acid on the gold nanoparticles-modified glassy carbon electrode[J]. Electrochimica Acta,2008,53:6610-6615. |
| APA | 胡广志,马永根,郭勇,&邵士俊.(2008).Electrocatalytic oxidation and simultaneous determination of uric acid and ascorbic acid on the gold nanoparticles-modified glassy carbon electrode.Electrochimica Acta,53,6610-6615. |
| MLA | 胡广志,et al."Electrocatalytic oxidation and simultaneous determination of uric acid and ascorbic acid on the gold nanoparticles-modified glassy carbon electrode".Electrochimica Acta 53(2008):6610-6615. |
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